Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiobenzoic Acid SCHEMBL7576129 | 0.81 | BCL2 (0.40) | BCL2BCL2L1ALOX5PLA2G1BATG4B | |
| SCHEMBL7584267 | 0.81 | MEN1 (0.58) | BCL2BCL2L1ALOX5MEN1KMT2A | |
| SCHEMBL7582708 | 0.80 | MEN1 (0.40) | BCL2BCL2L1MEN1KMT2AALDH1A1 | |
| SCHEMBL4219021 | 0.80 | PTPN1 (0.53) | BCL2BCL2L1ALOX5KMT2APTPN1 | |
| SCHEMBL6270999 | 0.79 | TSHR (0.49) | BCL2BCL2L1ALOX5ALDH1A1PTPN1 | |
| SCHEMBL7572805 | 0.78 | BCL2 (0.40) | BCL2BCL2L1ALOX5MEN1KMT2A | |
| SCHEMBL5802389 | 0.77 | PLA2G2A (0.46) | BCL2BCL2L1ALOX5LMNAHTT | |
| SCHEMBL7582814 | 0.77 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL2045956 | 0.77 | BCL2 (0.39) | BCL2BCL2L1ALOX5MEN1KMT2A | |
| SCHEMBL3068133 | 0.75 | BCL2 (0.40) | BCL2BCL2L1ALOX5HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458968-B2 | REACTING A CARBOXYLIC ACID COMPOUND WITH AN ALCOHOL OR MERCAPTAN, THEN PHOSPHORUS PENTASULFIDE | RENSSELAER POLYTECHNIC INSTITUTE | 2002-10-01 | — | — | US | claimed |
| US-20020019554-A1 | Dithiocarboxylic ester synthetic process | RENSSELAER POLYTECHNIC INSTITUTE | 2002-02-14 | — | — | US | claimed |
| US-6458968-B2 | REACTING A CARBOXYLIC ACID COMPOUND WITH AN ALCOHOL OR MERCAPTAN, THEN PHOSPHORUS PENTASULFIDE | RENSSELAER POLYTECHNIC INSTITUTE | 2002-10-01 | — | — | US | disclosed |
| US-20020019554-A1 | Dithiocarboxylic ester synthetic process | RENSSELAER POLYTECHNIC INSTITUTE | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019554-A1 | Dithiocarboxylic ester synthetic process | TST, PCCA, CTH | BCL2 4622/4885BCL2L1 4596/4885ALOX5 1038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.