Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 4/20 | 0.60 |
| ▸ | CA2 | P00918 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL253099 | 0.83 | CA1 (0.58) | MAPTTP53KDM4EMAPK1ALDH1A1 | |
| SCHEMBL606047 | 0.79 | MAPT (0.43) | MAPTTP53KDM4EMAPK1ALDH1A1 | |
| 3-Methoxycatechol SCHEMBL29477155 | 0.78 | TP53 (1.00) | MAPTTP53KDM4EMAPK1ALDH1A1 | |
| 3-Methoxycatechol SCHEMBL67332 | 0.78 | TP53 (1.00) | MAPTTP53KDM4EMAPK1ALDH1A1 | |
| SCHEMBL4136425 | 0.76 | CA1 (0.50) | MAPTTP53KDM4EMAPK1ALDH1A1 | |
| 3-Methoxycatechol SCHEMBL11796213 | 0.76 | TP53 (0.95) | MAPTTP53KDM4EMAPK1ALDH1A1 | |
| SCHEMBL16590519 | 0.76 | CA1 (0.50) | MAPTTP53KDM4EMAPK1ALDH1A1 | |
| SCHEMBL25874735 | 0.76 | CA1 (0.50) | MAPTTP53KDM4EMAPK1ALDH1A1 | |
| 1,2-Dimethoxybenzene SCHEMBL27631243 | 0.75 | CA2 (0.80) | MAPTTP53KDM4EMAPK1ALDH1A1 | |
| Guaiacol SCHEMBL29454477 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106831862-B | Chiral bridged axial chiral monophosphine ligand and preparation method thereof | 中山大学 | 2021-01-15 | — | — | CN | claimed |
| CN-106831862-A | Axial chirality monophosphorus ligand of one class chirality bridging and preparation method thereof | 中山大学 | 2017-06-13 | — | — | CN | claimed |
| US-11583527-B2 | Hydantoin derivatives useful as Kv3 inhibitors | AUTIFONY THERAPEUTICS LIMITED (GB) | 2023-02-21 | — | — | US | disclosed |
| US-11583527-B2 | Hydantoin derivatives useful as Kv3 inhibitors | AUTIFONY THERAPEUTICS LIMITED (GB) | 2023-02-21 | — | — | US | disclosed |
| US-11541052-B2 | Compounds | AUTIFONY THERAPEUTICS LIMITED (GB) | 2023-01-03 | — | — | US | disclosed |
| US-11541052-B2 | Compounds | AUTIFONY THERAPEUTICS LIMITED (GB) | 2023-01-03 | — | — | US | disclosed |
| US-20220054490-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2022-02-24 | — | — | US | disclosed |
| US-20220054490-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2022-02-24 | — | — | US | disclosed |
| US-11197859-B2 | Hydantoin derivatives useful as Kv3 inhibitors | AUTIFONY THERAPEUTICS LIMITED (GB) | 2021-12-14 | — | — | US | disclosed |
| US-11197859-B2 | Hydantoin derivatives useful as Kv3 inhibitors | AUTIFONY THERAPEUTICS LIMITED (GB) | 2021-12-14 | — | — | US | disclosed |
| US-20210023084-A1 | NOVEL COMPOUNDS | AUTIFONY SRL (IT) | 2021-01-28 | — | — | US | disclosed |
| US-20100041555-A1 | 3-Phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same | MITSUI CHEMICALS AGRO, INC. (JP) | 2010-02-18 | — | — | US | disclosed |
| US-7608563-B2 | 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same | MITSUI AGRO CHEMICALS, INC. (JP) | 2009-10-27 | — | — | US | disclosed |
| EP-1426365-B9 | 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME | MITSUI CHEMICALS AGRO INC (JP) | 2009-10-21 | — | — | EP | disclosed |
| EP-1426365-B1 | 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME | SANKYO AGRO CO LTD (JP) | 2009-07-15 | — | — | EP | disclosed |
| US-20050037925-A1 | 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same | SANKYO AGRO COMPANY, LIMITED (JP) | 2005-02-17 | — | — | US | disclosed |
| CN-1543455-A | 3-phenoxy-4-pyridazinol derivatives and herbicidal compositions containing the same | 三共农业株式会社 | 2004-11-03 | — | — | CN | disclosed |
| EP-1426365-A1 | 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME | Sankyo Agro Company, Limited (JP) | 2004-06-09 | — | — | EP | disclosed |
| CN-1130365-C | Alpha-1 adrenergic compounds, pharmaceutical compositions containing the same and uses thereof | ABBOTT CO (US) | 2003-12-10 | — | — | CN | disclosed |
| CN-1246861-A | Benzopyranopyrrole and benzopyranopyridine alpha-1 adrenergic compounds | ABBOTT LAB (US) | 2000-03-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11583527-B2 | Hydantoin derivatives useful as Kv3 inhibitors | KCNN3, KCND3, KCNA3 | MAPT 3926/4885TP53 4704/4885KDM4E 1460/4885 |
| US-20220054490-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | KCNN3, KCND3, KCNA3 | MAPT 3926/4885TP53 4704/4885KDM4E 1460/4885 |
| US-20100041555-A1 | 3-Phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same | CBR3, DDT, CBR1 | MAPT 4175/4885TP53 4121/4885KDM4E 923/4885 |
| US-11197859-B2 | Hydantoin derivatives useful as Kv3 inhibitors | KCNN3, KCND3, KCNA3 | MAPT 3926/4885TP53 4704/4885KDM4E 1460/4885 |
| US-20210023084-A1 | NOVEL COMPOUNDS | KCNN3, KCND3, KCNA3 | MAPT 2154/4885TP53 4850/4885KDM4E 2012/4885 |
| US-11541052-B2 | Compounds | KCNN3, KCNA3, KCNQ3 | MAPT 2485/4885TP53 4734/4885KDM4E 1888/4885 |
| US-20050037925-A1 | 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same | CBR3, DDT, CHRM2 | MAPT 3630/4885TP53 3824/4885KDM4E 960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.