Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1554681 | 0.86 | ALDH1A1 (0.43) | NOS1ALDH1A1LMNA | |
| SCHEMBL28747186 | 0.85 | MAOA (0.59) | MAOAMAOBCYP19A1SIGMAR1THRA | |
| SCHEMBL1818277 | 0.81 | ALDH1A1 (0.60) | MAOAMAOBCYP19A1SIGMAR1THRA | |
| SCHEMBL20321744 | 0.81 | MAOB (0.48) | MAOAMAOBCYP19A1SIGMAR1CYP3A4 | |
| SCHEMBL10907937 | 0.79 | DRD2 (0.55) | — | |
| SCHEMBL22527126 | 0.79 | MAOA (0.52) | MAOAMAOBCYP19A1SIGMAR1THRA | |
| SCHEMBL16335062 | 0.78 | HTR3E (0.54) | FFAR1ALDH1A1 | |
| SCHEMBL16335080 | 0.78 | TAAR1 (0.53) | MAOBSIGMAR1THRATHRBFFAR1 | |
| SCHEMBL26343229 | 0.78 | ALDH1A1 (0.37) | NOS1FFAR1ALDH1A1 | |
| SCHEMBL1026806 | 0.78 | MAOB (0.71) | MAOAMAOBCYP19A1SIGMAR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3562823-B1 | FUNCTIONALIZED NANOLUC INHIBITORS | PROMEGA CORP (US) | 2023-02-08 | — | — | EP | disclosed |
| EP-2861304-B1 | COMPOSITIONS COMPRISING HYALURONAN BIOSYNTHESIS PROMOTING AGENTS | SYMRISE AG (DE) | 2018-08-08 | — | — | EP | disclosed |