Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20463158 | 0.83 | GPR119 (0.40) | GPR119HSD11B1PIK3CDPIK3CA | |
| SCHEMBL5672385 | 0.77 | GPR119 (0.58) | GPR119PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL27394078 | 0.77 | GPR119 (0.58) | GPR119PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL5672367 | 0.77 | GPR119 (0.58) | GPR119PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL16980514 | 0.77 | GPR119 (0.58) | GPR119PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3401880 | 0.77 | GPR119 (0.58) | GPR119PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL28666814 | 0.76 | GPR119 (0.52) | GPR119PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL28666815 | 0.76 | GPR119 (0.52) | GPR119PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL21887083 | 0.75 | GPR119 (0.59) | GPR119PIK3CDPIK3CA | |
| SCHEMBL20234855 | 0.75 | GPR119 (0.59) | GPR119PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018144649-A1 | CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME | Arvinas, Inc. (US) | 2018-08-09 | — | — | WO | disclosed |