Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20463155 | 0.83 | GPR119 (0.46) | GPR119PIK3CDPIK3CAHSD11B1 | |
| SCHEMBL20231734 | 0.73 | GPR119 (0.41) | GPR119PIK3CDPIK3CAHSD11B1PDE4B | |
| SCHEMBL26774179 | 0.71 | GPR119 (0.59) | GPR119PIK3CDPIK3CA | |
| SCHEMBL26774174 | 0.71 | GPR119 (0.59) | GPR119PIK3CDPIK3CA | |
| SCHEMBL21887083 | 0.71 | GPR119 (0.59) | GPR119PIK3CDPIK3CA | |
| SCHEMBL5672367 | 0.70 | GPR119 (0.58) | GPR119PIK3CDPIK3CA | |
| SCHEMBL5672385 | 0.70 | GPR119 (0.58) | GPR119PIK3CDPIK3CA | |
| SCHEMBL20463156 | 0.69 | DDB1 (0.48) | GPR119PIK3CDPIK3CAHSD11B1 | |
| SCHEMBL28666815 | 0.69 | GPR119 (0.52) | GPR119PIK3CDPIK3CAUSP30 | |
| SCHEMBL28666814 | 0.69 | GPR119 (0.52) | GPR119PIK3CDPIK3CAUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018144649-A1 | CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME | Arvinas, Inc. (US) | 2018-08-09 | — | — | WO | disclosed |