Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.58 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.48 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.48 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.48 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.48 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.48 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.48 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.48 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.48 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.48 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.48 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.48 |
| ▸ | CACNA1E | Q15878 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5672367 | 1.00 | GPR119 (0.58) | GPR119PIK3CDPIK3CACACNB4CACNA1A | |
| SCHEMBL5270529 | 0.93 | GPR119 (0.51) | GPR119PIK3CDPIK3CACACNB4CACNA1A | |
| SCHEMBL2775134 | 0.93 | GPR119 (0.66) | GPR119CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL21887083 | 0.87 | GPR119 (0.59) | GPR119PIK3CDPIK3CANPBWR1MCHR1 | |
| SCHEMBL26774179 | 0.87 | GPR119 (0.59) | GPR119PIK3CDPIK3CANPBWR1MCHR1 | |
| SCHEMBL20234855 | 0.87 | GPR119 (0.59) | GPR119PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL26774174 | 0.87 | GPR119 (0.59) | GPR119PIK3CDPIK3CANPBWR1MCHR1 | |
| SCHEMBL3401880 | 0.86 | GPR119 (0.58) | GPR119PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL18089521 | 0.86 | GPR119 (0.58) | GPR119PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL22825652 | 0.86 | GPR119 (0.58) | GPR119PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7129243-B2 | Peptide compounds | ASTELLAS PHARMA INC. (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20040097425-A1 | Peptide compounds | ASTELLAS PHARMA INC. (JP) | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097425-A1 | Peptide compounds | VIP, NOS1, NOS3 | GPR119 118/4885PIK3CD 4803/4885PIK3CA 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.