Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 6/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11653795 | 0.71 | MEN1 (0.39) | CYP2B6MAPTCHRM2CHRM4CHRM5 | |
| SCHEMBL23374742 | 0.67 | CYP2D6 (0.46) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL2012096 | 0.67 | CACNA1F (0.33) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| Hydrochloric Acid SCHEMBL23246320 | 0.66 | GABRA1 (0.33) | MAPTCYP2D6CYP2C19MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL754670 | 0.66 | CACNA1F (0.33) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL6277129 | 0.66 | TAAR1 (0.43) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL28432834 | 0.66 | TAAR1 (0.43) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6681969 | 0.66 | TAAR1 (0.54) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL1538339 | 0.66 | TAAR1 (0.43) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL481608 | 0.65 | MAPK1 (0.46) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509584-B1 | PHARMACEUTICAL COMPOSITION FOR TREATING CUTANEOUS BURNS | 45 SEC LLC (US) | 2014-02-19 | — | — | EP | disclosed |
| EP-2509584-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING CUTANEOUS BURNS | 45 Sec. LLC (US) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011070168-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING CUTANEOUS BURNS | DEBETENCOURT JEAN-JACQUES (GB) | 2011-06-16 | — | — | WO | disclosed |