SCHEMBL6277129

SCHEMBL6277129

CC(C)CC(C)(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.43
MAPK1 P28482 1/20 0.41
CYP2D6 P10635 3/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 3/20 0.39
HIF1A Q16665 1/20 0.39
ALDH1A1 P00352 3/20 0.38
HSD17B10 Q99714 1/20 0.38
ALOX15 P16050 1/20 0.38
MEN1 O00255 1/20 0.38
CYP2C9 P11712 1/20 0.38
NPY2R P49146 1/20 0.38
KMT2A Q03164 1/20 0.38
RIPK1 Q13546 1/20 0.38
GRIN1 Q05586 4/20 0.37
GRIN2A Q12879 4/20 0.37
GRIN2D O15399 3/20 0.37
GRIN2C Q14957 3/20 0.37
GRIN2B Q13224 2/20 0.37
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1221602 0.82 MAOA (0.45) TAAR1CYP2D6CYP1A2
SCHEMBL1538339 0.81 TAAR1 (0.43) TAAR1MAPK1CYP2D6CYP2C19HIF1A
SCHEMBL6681969 0.81 TAAR1 (0.54) TAAR1MAPK1CYP2D6CYP2C19HIF1A
SCHEMBL873678 0.79 CYP2C19 (0.46) TAAR1CYP2D6CYP1A2CYP2C19HIF1A
SCHEMBL10868295 0.79 CYP2C19 (0.42) TAAR1MAPK1CYP2D6CYP1A2CYP2C19
SCHEMBL17885863 0.79 ALDH1A1 (0.44) TAAR1MAPK1CYP2D6CYP2C19HIF1A
SCHEMBL16590934 0.78 MAPK1 (0.36) TAAR1MAPK1CYP2D6CYP1A2CYP2C19
SCHEMBL24059137 0.77 CYP2C19 (0.41) TAAR1MAPK1CYP2D6CYP1A2CYP2C19
SCHEMBL21189697 0.77
SCHEMBL8558582 0.77 TSHR (0.42) TAAR1MAPK1CYP2D6CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6967229-B2 Carbon-carbon initiators for use in golf balls ACUSHNET COMPANY (US) 2005-11-22 US claimed
US-20050009992-A1 Carbon-carbon initiators for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US claimed
US-9056227-B2 Golf ball comprising a core having a shallow hardness gradient ACUSHNET COMPANY (US) 2015-06-16 US disclosed
US-8968117-B2 Dual-core comprising zero gradient center and positive gradient outer core layer ACUSHNET COMPANY (US) 2015-03-03 US disclosed
CN-103877703-A Dual-Core Comprising Zero Gradient Center And Positive Gradient Outer Core Layer ACUSHNET CO 2014-06-25 CN disclosed
US-20130109504-A1 DUAL-CORE COMPRISING ZERO GRADIENT CENTER AND POSITIVE GRADIENT OUTER CORE LAYER ACUSHNET COMPANY (US) 2013-05-02 US disclosed
US-20130109506-A1 GOLF BALL COMPRISING A CORE HAVING A SHALLOW HARDNESS GRADIENT ACUSHNET COMPANY (US) 2013-05-02 US disclosed
US-6967229-B2 Carbon-carbon initiators for use in golf balls ACUSHNET COMPANY (US) 2005-11-22 US disclosed
US-20050009992-A1 Carbon-carbon initiators for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US disclosed
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed
EP-0322669-B1 DRY LIQUID ANALYSIS ELEMENT FUJI PHOTO FILM CO., LTD. (JP) 1993-08-11 EP disclosed
US-5122451-A Easy permeation of high molecular weight component FUJI PHOTO FILM LTD. (JP) 1992-06-16 US disclosed
EP-0322669-A1 Dry liquid analysis element FUJI PHOTO FILM CO., LTD. (JP) 1989-07-05 EP disclosed