Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL324374 | 0.83 | TAAR1 (0.47) | TAAR1MAPK1CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL4399836 | 0.82 | TAAR1 (0.50) | TAAR1MAPK1CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL10831632 | 0.82 | TAAR1 (0.56) | TAAR1 | |
| SCHEMBL4399833 | 0.82 | TAAR1 (0.50) | TAAR1MAPK1CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL113841 | 0.82 | TAAR1 (0.50) | TAAR1MAPK1CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL6277129 | 0.81 | TAAR1 (0.43) | TAAR1MAPK1CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL1538339 | 0.81 | TAAR1 (0.43) | TAAR1MAPK1CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL1019329 | 0.80 | RIPK1 (0.52) | TAAR1MAPK1ALDH1A1ALOX15RIPK1 | |
| SCHEMBL18900864 | 0.80 | GAA (0.39) | TAAR1MAPK1CYP3A4HIF1AALDH1A1 | |
| SCHEMBL17885863 | 0.79 | ALDH1A1 (0.44) | TAAR1MAPK1CYP2D6CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11225480-B2 | Malic enzyme inhibitors | SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) | 2022-01-18 | — | — | US | disclosed |
| US-20210163454-A1 | SMALL MOLECULE INHIBITORS OF EBOLA AND LASSA FEVER VIRUSES AND METHODS OF USE | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 2021-06-03 | — | — | US | disclosed |
| US-20210115038-A1 | MALIC ENZYME INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) | 2021-04-22 | — | — | US | disclosed |
| EP-0985649-B1 | Method for producing an aromatic compound having an alkyl group with at least three carbon atoms | TORAY INDUSTRIES (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6462248-B1 | THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS | TORAY INDUSTRIES, INC. (JP) | 2002-10-08 | — | — | US | disclosed |
| EP-0985649-A2 | Method for producing an aromatic compound having an alkyl group with at least three carbon atoms | TORAY INDUSTRIES, INC. (JP) | 2000-03-15 | — | — | EP | disclosed |
| US-5175135-A | Using acid mordenite zeolite as alkylation catalysts to produce dialkylbiphenyl | THE DOW CHEMICAL COMPANY (US) | 1992-12-29 | — | — | US | disclosed |
| US-5004841-A | Para-substitutions with crystalline acidic mordenite zeolite alkylation catalysts | THE DOW CHEMICAL COMPANY (US) | 1991-04-02 | — | — | US | disclosed |
| EP-0317907-A2 | Alkylation of polycyclic aromatic compounds to alkylates enriched in the para-substituted isomers | THE DOW CHEMICAL COMPANY (US) | 1989-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210115038-A1 | MALIC ENZYME INHIBITORS | ME1, ME2, ME3 | TAAR1 4603/4885MAPK1 1199/4885CYP2D6 1759/4885 |
| US-11225480-B2 | Malic enzyme inhibitors | ME1, RNASE1, ME2 | TAAR1 3983/4885MAPK1 378/4885CYP2D6 981/4885 |
| US-20210163454-A1 | SMALL MOLECULE INHIBITORS OF EBOLA AND LASSA FEVER VIRUSES AND METHODS OF USE | CCR8, RPS8, HDHD5 | TAAR1 298/4885MAPK1 4246/4885CYP2D6 3342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.