⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL112040 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL10426264 | 0.77 | ALDH1A1 (0.62) | — | |
| Ammonia Solution, Strong SCHEMBL1640555 | 0.77 | ALDH1A1 (0.62) | — | |
| Fluoride SCHEMBL28877073 | 0.77 | ALDH1A1 (0.62) | — | |
| SCHEMBL17065148 | 0.76 | CES1 (0.38) | — | |
| SCHEMBL11762263 | 0.74 | ALDH1A1 (0.52) | — | |
| SCHEMBL329345 | 0.72 | — | — | |
| SCHEMBL251582 | 0.72 | — | — | |
| Chloroform SCHEMBL9943936 | 0.72 | ALDH1A1 (0.56) | — | |
| SCHEMBL50045 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265439-B1 | PROCESS FOR PREPARING 3-CHLORO-2-VINYLPHENYLSULFONATES | BAYER CROPSCIENCE AG (DE) | 2019-03-27 | — | — | EP | claimed |
| US-20100234343-A1 | INHIBITORS OF ION CHANNELS | ICAGEN, INC. (US) | 2010-09-16 | — | — | US | claimed |
| US-7705158-B2 | Inhibitors of ion channels | ICAGEN, INC. (US) | 2010-04-27 | — | — | US | claimed |
| CN-105566530-A | Process for preparing ethylene homopolymers or copolymers of ethylene and alpha-olefins using transition metal catalysts composition | SABIC SK NEXLENE COMPANY PTE LTD | 2016-05-11 | — | — | CN | disclosed |
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |
| EP-2702042-A1 | NOVEL BICYCLIC NITROGEN CONTAINING HETEROARYL TGR5 RECEPTOR MODULATORS | Bristol-Myers Squibb Company (US) | 2014-03-05 | — | — | EP | disclosed |
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-8338608-B2 | Inhibitors of ion channels | ICAGEN INC. (US) | 2012-12-25 | — | — | US | disclosed |
| WO-2012149236-A1 | NOVEL BICYCLIC NITROGEN CONTAINING HETEROARYL TGR5 RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-11-01 | — | — | WO | disclosed |
| US-8163753-B2 | 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| EP-1165500-A1 | AMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES,TNF-ALPHA,AND AGGRECANASE | Du Pont Pharmaceuticals Company (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059874-A1 | NOVEL AMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES, TNF-α, AND AGGRECANASE | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-10-12 | — | — | WO | disclosed |
| EP-1028945-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AS ANTI-INFLAMMATORY AGENTS | Amgen Inc. (US) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999024404-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AS ANTI-INFLAMMATORY AGENTS | AMGEN INC. (US) | 1999-05-20 | — | — | WO | disclosed |
| US-4300942-A | N-(Substituted carbonyl) derivatives of N-phos-phinylmethylglycinates and the herbicidal use thereof | MONSANTO COMPANY (US) | 1981-11-17 | — | — | US | disclosed |
| US-4251258-A | N-(Substituted carbonyl) derivatives of N-phosphinylmethylglycinates and the herbicidal use thereof | MONSANTO COMPANY (US) | 1981-02-17 | — | — | US | disclosed |
| US-4211732-A | N-Carbobenzoxy-N-phosphinothioylmethylgylcine esters | MONSANTO COMPANY (US) | 1980-07-08 | — | — | US | disclosed |
| US-4211548-A | Esters of N-phosphinothioylmethylglycine and herbicidal method | MONSANTO COMPANY (US) | 1980-07-08 | — | — | US | disclosed |
| US-4195983-A | HERBICIDES | MONSANTO COMPANY (US) | 1980-04-01 | — | — | US | disclosed |