Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.55 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | IDH1 | O75874 | 17/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20465159 | 0.89 | L3MBTL1 (0.56) | RPS6KB1RORCIDH1 | |
| SCHEMBL18477024 | 0.87 | RORC (0.64) | RPS6KB1RORCIDH1KDM4E | |
| SCHEMBL20465151 | 0.84 | RORC (0.58) | RPS6KB1RORCIDH1 | |
| SCHEMBL18477019 | 0.79 | RPS6KB1 (0.55) | RPS6KB1IDH1KDM4E | |
| SCHEMBL18477022 | 0.78 | RORC (0.60) | RPS6KB1RORCIDH1 | |
| SCHEMBL21311021 | 0.75 | RPS6KB1 (0.57) | RPS6KB1IDH1KDM4E | |
| SCHEMBL20465158 | 0.74 | RORC (0.63) | RORC | |
| SCHEMBL15550938 | 0.72 | HRH3 (0.53) | KDM4E | |
| SCHEMBL15550939 | 0.72 | HRH3 (0.53) | KDM4E | |
| SCHEMBL30158822 | 0.72 | MEN1 (0.56) | RPS6KB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180222860-A1 | MODULATORS OF ROR-GAMMA | VITAE PHARMACEUTICALS, LLC | 2018-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180222860-A1 | MODULATORS OF ROR-GAMMA | RORB, RORC, RORA | RPS6KB1 191/4885RORC 2/4885IDH1 3584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.