Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | PAM | P19021 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20466247 | 0.89 | EPHX2 (0.46) | DGKAMGLLHDAC3HDAC4HDAC1 | |
| SCHEMBL823903 | 0.87 | EPHX2 (0.44) | DGKAMGLLHDAC3HDAC4HDAC1 | |
| SCHEMBL8719563 | 0.85 | MGLL (0.39) | DGKAMGLLDNM1ACHETSHR | |
| SCHEMBL20466249 | 0.83 | DGKA (0.49) | DGKAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12565651 | 0.81 | DGKA (0.60) | DGKAMGLLDNM1EPHX2PAM | |
| SCHEMBL176410 | 0.81 | DGKA (0.60) | DGKAMGLLDNM1EPHX2PAM | |
| SCHEMBL12565648 | 0.81 | DGKA (0.60) | DGKAMGLLDNM1EPHX2PAM | |
| SCHEMBL8065894 | 0.81 | DGKA (0.60) | DGKAMGLLDNM1EPHX2PAM | |
| SCHEMBL12565650 | 0.81 | DGKA (0.60) | DGKAMGLLDNM1EPHX2PAM | |
| SCHEMBL821972 | 0.81 | DGKA (0.60) | DGKAMGLLDNM1EPHX2PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180221498-A1 | PH-SENSITIVE LINKERS FOR DELIVERING A THERAPEUTIC AGENT | GNT BIOTECH & MEDICALS CORPORATION (TW) | 2018-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180221498-A1 | PH-SENSITIVE LINKERS FOR DELIVERING A THERAPEUTIC AGENT | CD47, CD44, ASIC1 | DGKA 2761/4885MGLL 4636/4885HDAC3 1276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.