Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16755705 | 0.92 | HSD17B10 (0.33) | ALDH1A1CYP3A4THRBHPGDTSHR | |
| SCHEMBL16755710 | 0.65 | MEN1 (0.33) | ALDH1A1THRBMAPK1CASP1RECQL | |
| SCHEMBL20080292 | 0.65 | ADRA2A (0.32) | ALDH1A1MAPK1CASP1 | |
| SCHEMBL13019593 | 0.62 | PRMT1 (0.42) | ALDH1A1CYP3A4THRBHPGDTSHR | |
| SCHEMBL20080328 | 0.59 | — | — | |
| SCHEMBL20099468 | 0.57 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL16755701 | 0.56 | MAPT (0.62) | ALDH1A1CYP3A4THRBHPGDMAPK1 | |
| SCHEMBL20225302 | 0.56 | MAPT (0.44) | ALDH1A1MAPK1CASP1HSD17B10 | |
| SCHEMBL16755694 | 0.55 | MAPT (0.64) | ALDH1A1CYP3A4THRBHPGDMAPK1 | |
| SCHEMBL8163979 | 0.55 | PRMT1 (0.50) | ALDH1A1CYP3A4THRBHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180222880-A1 | SecA INHIBITORS AND METHODS OF MAKING AND USING THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180222880-A1 | SecA INHIBITORS AND METHODS OF MAKING AND USING THEREOF | SEC61B, SEC61A1, SEC23A | ALDH1A1 4172/4885CYP3A4 2912/4885THRB 3592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.