SCHEMBL2046871

SCHEMBL2046871

CC1=Cc2c(C)cc(C)cc2C1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29773511 1.00 RAPGEF4 (0.32) RAPGEF4CYP1A2CYP2A6
SCHEMBL22228249 0.98 RAPGEF4 (0.31) RAPGEF4CYP1A2CYP2A6
Lithium SCHEMBL29650729 0.98 RAPGEF4 (0.31) RAPGEF4CYP1A2CYP2A6
Hydrochloric Acid SCHEMBL28063714 0.96 RAPGEF4 (0.30) RAPGEF4
SCHEMBL28063713 0.92
SCHEMBL2965293 0.78
SCHEMBL2971055 0.78 TAS1R3 (0.32)
SCHEMBL7464131 0.77
SCHEMBL28314871 0.75 BRD9 (0.34)
SCHEMBL7095350 0.75 L3MBTL1 (0.38) CYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111454389-B Catalyst composition for polymerization of polyolefin, method for preparing polyolefin, and polyolefin resin DL化学株式会社 2022-07-15 CN disclosed
US-11332553-B2 Catalyst composition for polymerizing polyolefin, method for producing polyolefin, and polyolefin resin DL CHEMICAL CO., LTD. (KR) 2022-05-17 US disclosed
EP-3686223-A2 CATALYST COMPOSITION FOR POLYMERIZING POLYOLEFIN, METHOD FOR PRODUCING POLYOLEFIN, AND POLYOLEFIN RESIN Daelim Industrial Co., Ltd. (KR) 2020-07-29 EP disclosed
CN-111454389-A Catalyst composition for polymerization of polyolefin, process for producing polyolefin, and polyolefin resin 大林产业株式会社 2020-07-28 CN disclosed
US-20200231717-A1 CATALYST COMPOSITION FOR POLYMERIZING POLYOLEFIN, METHOD FOR PRODUCING POLYOLEFIN, AND POLYOLEFIN RESIN DL CHEMICAL CO., LTD. (KR) 2020-07-23 US disclosed
EP-1622948-B1 PROCESS FOR POLYMERIZING 1-BUTENE BASELL POLYOLEFINE GMBH (DE) 2019-11-20 EP disclosed
CN-103641863-B A kind of bridged combined metal complex and application thereof ZHEJIANG UNIVERSITY (CN) 2016-05-11 CN disclosed
US-8178636-B2 Process for the preparation of atactic 1-butene polymers BASELL POLYOLEFINE GMBH (DE) 2012-05-15 US disclosed
US-7964679-B2 1-Butene polymer polymerization catalyst system: a Hf, Ti or Zr metallocene having an indene ring and a fluorene ring bridged by a silane group; an alumoxane or a compound that forms an alkyl metallocene cation; and an organoaluminum compound; (2,4,6-trimethylindenyl)(9-fluorenyl)dimethylsilane BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2011-06-21 US disclosed
EP-2223944-A1 Process for producing semicrystalline propylene polymers Borealis AG (AT) 2010-09-01 EP disclosed
US-5576260-A POLYMERIZATION CATALYSTS FOR OLEFINS HOECHST AKTIENGESELLSCHAFT (DE) 1996-11-19 US disclosed
US-5532396-A HAS TWO INDENYL LIGANDS WITH DIFFERENT SUBSTITUTION PATTERNS ON THE SIX-MEMBERED RINGS. LIGANDS ARE JOINED BY DIVALENT GROUP CONNECTING FIVE-MEMBERED RINGS. METAL IS FROM GROUP /IVB/, /VB/ OR /VIB/. OLEFIN POLYMERIZATION CATALYST HOECHST AKTIENGESELLSCHAFT (DE) 1996-07-02 US disclosed
EP-0693506-A2 Process for the preparation of amorphous polymers of propylene SPHERILENE S.p.A. (IT) 1996-01-24 EP disclosed
EP-0659757-A1 Metallocenes HOECHST AKTIENGESELLSCHAFT (DE) 1995-06-28 EP disclosed
US-5374752-A Catalyst system containing metallocene HOECHST AKTIENGESELLSCHAFT (DE) 1994-12-20 US disclosed
US-5360921-A REACTING LITHIUM, SODIUM OR POTASSIUM SALT OF A CYCLOPENTADIENE DERIVATIVE WITH A SILICON OR GERMANIUM HALIDE COMPOUND IN THE PRESENCE OF A CYANIDE OR A THIOCYANATE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-11-01 US disclosed
EP-0617044-A2 Process for preparing cyclopentadienyl group-containing silicon compound or cyclopentadienyl group-containing germanium compound MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-09-28 EP disclosed
US-5328969-A Cocatalyst of an aluminoxane and metallocene HOECHST AKTIENGELLSCHAFT (DE) 1994-07-12 US disclosed
EP-0545303-A1 Process for preparing high molecular weight polyolefins HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-09 EP disclosed
EP-0545304-A1 Process for the preparation of substituted indenes and their use as ligands for metallocene catalysts HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-09 EP disclosed