SCHEMBL22228249

SCHEMBL22228249

CC1=Cc2c(C)cc(C)cc2C1.[LiH]

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29773511 0.98 RAPGEF4 (0.32) RAPGEF4CYP1A2CYP2A6
SCHEMBL2046871 0.98 RAPGEF4 (0.32) RAPGEF4CYP1A2CYP2A6
Lithium SCHEMBL29650729 0.96 RAPGEF4 (0.31) RAPGEF4CYP1A2CYP2A6
Hydrochloric Acid SCHEMBL28063714 0.94 RAPGEF4 (0.30) RAPGEF4
SCHEMBL28063713 0.90
SCHEMBL2971055 0.77 TAS1R3 (0.32)
SCHEMBL2965293 0.77
SCHEMBL7464131 0.75
SCHEMBL28314871 0.74 BRD9 (0.34)
SCHEMBL4194603 0.74 ALDH1A1 (0.35) RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111454389-B Catalyst composition for polymerization of polyolefin, method for preparing polyolefin, and polyolefin resin DL化学株式会社 2022-07-15 CN disclosed
US-11332553-B2 Catalyst composition for polymerizing polyolefin, method for producing polyolefin, and polyolefin resin DL CHEMICAL CO., LTD. (KR) 2022-05-17 US disclosed
EP-3686223-A2 CATALYST COMPOSITION FOR POLYMERIZING POLYOLEFIN, METHOD FOR PRODUCING POLYOLEFIN, AND POLYOLEFIN RESIN Daelim Industrial Co., Ltd. (KR) 2020-07-29 EP disclosed
CN-111454389-A Catalyst composition for polymerization of polyolefin, process for producing polyolefin, and polyolefin resin 大林产业株式会社 2020-07-28 CN disclosed
US-20200231717-A1 CATALYST COMPOSITION FOR POLYMERIZING POLYOLEFIN, METHOD FOR PRODUCING POLYOLEFIN, AND POLYOLEFIN RESIN DL CHEMICAL CO., LTD. (KR) 2020-07-23 US disclosed