Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CES1 | P23141 | 6/20 | 0.36 |
| ▸ | CES2 | O00748 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4340186 | 0.85 | ALDH1A1 (0.38) | ALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL704158 | 0.81 | ALDH1A1 (0.44) | ALDH1A1CES1CES2LMNAHSD17B10 | |
| SCHEMBL705411 | 0.79 | NAAA (0.43) | ALDH1A1CES1CES2LMNATSHR | |
| SCHEMBL11492778 | 0.74 | ALDH1A1 (0.43) | ALDH1A1CES1CES2HSD17B10FAAH | |
| SCHEMBL4235733 | 0.74 | — | — | |
| SCHEMBL18496521 | 0.73 | ALDH1A1 (0.41) | ALDH1A1CES1CES2HSD17B10FAAH | |
| SCHEMBL18496519 | 0.73 | ALDH1A1 (0.41) | ALDH1A1CES1CES2HSD17B10FAAH | |
| SCHEMBL21326396 | 0.73 | KDM4C (0.38) | LMNAFAAHCA1 | |
| SCHEMBL705156 | 0.70 | ALDH1A1 (0.38) | ALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL8523289 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8344087-B2 | Hydrosilylation cured organosiloxanes having diluent therein | DOW CORNING CORPORATION (US) | 2013-01-01 | — | — | US | disclosed |
| EP-1866377-B1 | ORGANOSILOXANE COMPOSITIONS | DOW CORNING (US) | 2012-06-27 | — | — | EP | disclosed |
| CN-101151325-B | Organosiloxane compositions | DOW CORNING INC | 2012-04-11 | — | — | CN | disclosed |
| US-8088857-B2 | Organosiloxane compositions | DOW CORNING CORPORATION (US) | 2012-01-03 | — | — | US | disclosed |
| CN-101151329-B | Organosiloxane compositions | DOW CORNING CORP. (US) | 2011-12-07 | — | — | CN | disclosed |
| US-8067519-B2 | Organosiloxane compositions | DOW CORNING CORPORATION (US) | 2011-11-29 | — | — | US | disclosed |
| US-20110003081-A1 | Organosiloxane Compositions | DOW SILICONES CORPORATION | 2011-01-06 | — | — | US | disclosed |
| US-7754800-B2 | Organosiloxane compositions | DOW CORNING EUROPE SA (BE) | 2010-07-13 | — | — | US | disclosed |
| US-20080312367-A1 | Organosiloxane Compositions | DOW SILICONES CORPORATION | 2008-12-18 | — | — | US | disclosed |
| US-20080284106-A1 | Diluted polymer with hydrolyzable end groups obtained by polymerization in the presence of an organic extender and/or plasticizer; crosslinking agent, condensation catalyst; sealants with low modulus and high elongation | DOW SILICONES CORPORATION | 2008-11-20 | — | — | US | disclosed |
| CN-101151329-A | Organosiloxane compositions | DOW CORNING (US) | 2008-03-26 | — | — | CN | disclosed |
| CN-101151325-A | Organosiloxane compositions | DOW CORNING (US) | 2008-03-26 | — | — | CN | disclosed |
| EP-1866377-A1 | ORGANOSILOXANE COMPOSITIONS | Dow Corning Corporation (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006107762-A1 | ORGANOSILOXANE COMPOSITIONS | DOW CORNING CORPORATION (US) | 2006-10-12 | — | — | WO | disclosed |