SCHEMBL964754

SCHEMBL964754

C=CC(=O)Nc1ccc(S(=O)(=O)c2ccc(N)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 11/20 0.64
PKM P14618 1/20 0.64
CYP2C19 P33261 1/20 0.64
F13A1 P00488 5/20 0.58
TGM1 P22735 5/20 0.58
PRMT1 Q99873 3/20 0.57
LMNA P02545 2/20 0.53
TGM3 Q08188 1/20 0.53
CA12 O43570 2/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA9 Q16790 2/20 0.53
SETD7 Q8WTS6 1/20 0.52
CYP3A4 P08684 2/20 0.52
CYP2C9 P11712 2/20 0.52
MPO P05164 1/20 0.52
TSHR P16473 1/20 0.52
HTR6 P50406 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6481884 0.88 TGM2 (0.66) TGM2PKMF13A1TGM1LMNA
SCHEMBL7785803 0.88 TGM2 (0.66) TGM2PKMF13A1TGM1LMNA
SCHEMBL29054310 0.88 TGM2 (0.66) TGM2PKMF13A1TGM1LMNA
SCHEMBL7894169 0.85 TGM2 (0.66) TGM2F13A1TGM1PRMT1LMNA
SCHEMBL19457348 0.84 TGM2 (0.77) TGM2PKMF13A1TGM1LMNA
SCHEMBL20885056 0.83 TGM2 (0.63) TGM2PKMCYP2C19F13A1TGM1
SCHEMBL20469814 0.83 TGM2 (0.59) TGM2PKMF13A1TGM1LMNA
SCHEMBL17327893 0.83 TGM2 (0.69) TGM2F13A1TGM1LMNATGM3
SCHEMBL202328 0.81 TGM2 (0.70) TGM2F13A1TGM1LMNATGM3
Acetic Acid SCHEMBL11194307 0.81 TGM2 (0.62) TGM2PKMCYP2C19F13A1TGM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11111320-B2 Addition-fragmentation oligomers 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-09-07 US disclosed
CN-107406723-B Addition-fragmentation oligomers 3M创新有限公司 2021-05-07 CN disclosed
EP-2675783-B1 ADDITION-FRAGMENTATION AGENTS 3M INNOVATIVE PROPERTIES CO (US) 2020-04-22 EP disclosed
EP-3259323-B1 ADDITION-FRAGMENTATION OLIGOMERS 3M INNOVATIVE PROPERTIES CO (US) 2020-02-26 EP disclosed
US-20200031961-A1 ADDITION-FRAGMENTATION OLIGOMERS 3M INNOVATIVE PROPERTIES CO (US) 2020-01-30 US disclosed
US-10479848-B2 Addition-fragmentation oligomers 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-11-19 US disclosed
US-10370322-B2 Addition-fragmentation agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-08-06 US disclosed
EP-3502092-A1 ADDITION-FRAGMENTATION AGENTS 3M Innovative Properties Company (US) 2019-06-26 EP disclosed
EP-2931756-B1 ADDITION-FRAGMENTATION OLIGOMERS 3M INNOVATIVE PROPERTIES CO (US) 2018-08-08 EP disclosed
EP-3058014-B1 ALLYL DISULFIDE-CONTAINING ADDITION-FRAGMENTATION OLIGOMERS 3M INNOVATIVE PROPERTIES CO (US) 2018-06-20 EP disclosed
WO-2003015720-A1 HARDENABLE SELF-SUPPORTING STRUCTURES AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-02-27 WO disclosed
WO-2002102909-A1 REACTIVE OLIGOMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-12-27 WO disclosed
US-20020132927-A1 Pressure sensitive adhesives possessing high load bearing capability 3M INNOVATIVE PROPERTIES COMPANY 2002-09-19 US disclosed
US-6448337-B1 CURABLE SYRUP COMPRISING DUAL POLYMERS CONTAINING PENDANT INTERREACTIVE GROUPS, FREE RADICAL POLYMERIZABLE SOLVENT MONOMER AND PHOTOINITIATOR; BALANCED ADHESIVE AND COHESIVE CHARACTERISTICS 3M INNOVATIVE PROPERTIES COMPANY 2002-09-10 US disclosed
EP-1230315-A1 PRESSURE SENSITIVE ADHESIVES POSSESSING HIGH LOAD BEARING CAPABILITY 3M Innovative Properties Company (US) 2002-08-14 EP disclosed
WO-2002038694-A1 PRESSURE SENSITIVE ADHESIVES POSSESSING HIGH LOAD BEARING CAPABILITY 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-05-16 WO disclosed
EP-0808348-B1 CROSS-LINKABLE PRESSURE SENSITIVE ADHESIVE AND PROCESS FOR THE PRODUCTION OF AN ARTICLE COATED WITH A CROSSLINKED PRESSURE SENSITIVE ADHESIVE MINNESOTA MINING & MFG (US) 1999-05-06 EP disclosed
US-5741543-A CONTAINING UNSATURATED MONOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-04-21 US disclosed
EP-0808348-A1 PROCESS FOR THE PRODUCTION OF AN ARTICLE COATED WITH A CROSSLINKED PRESSURE SENSITIVE ADHESIVE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-11-26 EP disclosed
WO-1996024644-A1 PROCESS FOR THE PRODUCTION OF AN ARTICLE COATED WITH A CROSSLINKED PRESSURE SENSITIVE ADHESIVE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-08-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10479848-B2 Addition-fragmentation oligomers ECPAS, ITGA8, NBAS TGM2 1638/4885PKM 4286/4885CYP2C19 4275/4885
US-10370322-B2 Addition-fragmentation agents NR4A1, PARP14, MTX1 TGM2 4329/4885PKM 3917/4885CYP2C19 4208/4885
US-20200031961-A1 ADDITION-FRAGMENTATION OLIGOMERS ECPAS, ITGA8, NBAS TGM2 1638/4885PKM 4286/4885CYP2C19 4275/4885
US-11111320-B2 Addition-fragmentation oligomers ECPAS, ITGA8, NBAS TGM2 1638/4885PKM 4286/4885CYP2C19 4275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.