Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 8/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12513634 | 0.81 | SLC6A2 (0.54) | HRH3SLC6A2SLC6A3KCNH2ALDH1A1 | |
| SCHEMBL9766077 | 0.71 | SIGMAR1 (0.54) | KDM4EMEN1KMT2A | |
| SCHEMBL22308386 | 0.70 | NPC1 (0.46) | KCNH2CYP11B1CYP11B2 | |
| SCHEMBL12320871 | 0.69 | NPC1 (0.49) | KCNH2CYP11B1CYP11B2 | |
| SCHEMBL14435697 | 0.69 | TP53 (0.48) | HRH3SLC6A2SLC6A3KCNH2TP53 | |
| SCHEMBL13561473 | 0.69 | P2RX7 (0.50) | SLC6A2SLC6A3ALDH1A1KDM4ETSHR | |
| Hydrochloric Acid SCHEMBL28462217 | 0.68 | NPC1 (0.45) | KCNH2CYP11B1CYP11B2 | |
| SCHEMBL10601133 | 0.68 | CYP1A2 (0.62) | HRH3SLC6A2SLC6A3KCNH2ALDH1A1 | |
| SCHEMBL113896 | 0.68 | CYP1A2 (0.62) | HRH3SLC6A2SLC6A3KCNH2ALDH1A1 | |
| SCHEMBL10598753 | 0.66 | OPRM1 (0.63) | HRH3SLC6A2SLC6A3KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018152554-A1 | ANTITUSSIVE COMPOSITIONS AND METHODS | ATTENUA, INC. (US) | 2018-08-23 | — | — | WO | disclosed |