Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15516443 | 0.81 | KDM4E (0.47) | KDM4ECYP3A4CYP2C19HIF1ALMNA | |
| SCHEMBL15517013 | 0.81 | LMNA (0.51) | LMNAMAPT | |
| SCHEMBL29420516 | 0.71 | MAOA (0.54) | KDM4ECYP3A4CYP2C19MAPT | |
| SCHEMBL397020 | 0.71 | MAOA (0.54) | KDM4ECYP3A4CYP2C19MAPT | |
| SCHEMBL15516646 | 0.71 | AXL (0.41) | KDM4ECYP2C19MAPT | |
| SCHEMBL5638415 | 0.69 | POLB (0.50) | — | |
| SCHEMBL30415489 | 0.69 | POLB (0.50) | — | |
| SCHEMBL6232953 | 0.69 | CRHBP (0.32) | — | |
| SCHEMBL1392180 | 0.68 | — | — | |
| SCHEMBL246231 | 0.68 | LATS1 (0.43) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018151678-A1 | COMPOUNDS FOR TREATMENT OF CANCER AND EPIGENETICS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-08-23 | — | — | WO | claimed |
| WO-2018151678-A1 | COMPOUNDS FOR TREATMENT OF CANCER AND EPIGENETICS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-08-23 | — | — | WO | disclosed |