SCHEMBL2048192

SCHEMBL2048192

CC1(C)CC[Si](c2ccccc2)(c2ccccc2)OC1(C)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 4/20 0.36
DRD4 P21917 1/20 0.36
OPRK1 P41145 2/20 0.33
OPRL1 P41146 1/20 0.33
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
PAX8 Q06710 1/20 0.32
MCL1 Q07820 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
SLC6A4 P31645 2/20 0.31
SLC22A1 O15245 1/20 0.31
ADRA1A P35348 1/20 0.31
OPRD1 P41143 1/20 0.31
KCNH2 Q12809 1/20 0.31
DPP4 P27487 1/20 0.31
AKR1C1 Q04828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2232615 0.85 OPRM1 (0.35) OPRM1DRD4OPRK1OPRL1ALDH1A1
SCHEMBL27962277 0.82 DRD4 (0.31) OPRM1DRD4
SCHEMBL9751915 0.81 OPRM1 (0.32) OPRM1DRD4OPRK1OPRL1MAOA
SCHEMBL23748538 0.78 TSHR (0.33) OPRM1DRD4OPRK1OPRL1ALDH1A1
SCHEMBL28026738 0.76 DRD4 (0.30) OPRM1DRD4
SCHEMBL182249 0.71
SCHEMBL28711657 0.71 AKR1C1 (0.30) AKR1C1
SCHEMBL27767618 0.71
SCHEMBL2352430 0.70 AKR1C1 (0.35) SLC6A4DPP4AKR1C1SLC6A2SLC6A3
Ammonia Solution, Strong SCHEMBL7586755 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112654728-A Resin molded article with metal film and method for producing same 三菱工程塑料株式会社 2021-04-13 CN disclosed
WO-2020054705-A1 METAL-COATED MOLDED RESIN ARTICLES AND PRODUCTION METHOD THEREFOR 三菱エンジニアリングプラスチックス株式会社 2020-03-19 WO disclosed
EP-1595920-B1 Polymer alloy, thermoplastic resin composition, and molded article TORAY INDUSTRIES (JP) 2015-01-07 EP disclosed
US-8210213-B2 Multilayer tube WINTECH POLYMER LTD. (JP) 2012-07-03 US disclosed
US-7960464-B2 Thermoplastic resin composition and molded article TORAY INDUSTRIES, INC. (JP) 2011-06-14 US disclosed
US-7652079-B2 Containing polybutylene terephthalate, isophthalic acid modified polybutylene terephthalate or polyethylene terephthalate, ethylene-glycidyl methacrylate or ethylene-(meth)acrylate-glycidyl methacrylate terpolymer, glass fiber and boron nitride; heat shockproof; electric/electronic parts; moldings WINTECH POLYMER LTD. (JP) 2010-01-26 US disclosed
US-20090246434-A1 MULTILAYER TUBE WINTECH POLYMER LTD. (JP) 2009-10-01 US disclosed
US-20080226857-A1 Thermoplastic resin composition and molded article KOBAYASHI SADAYUKI 2008-09-18 US disclosed
US-7385013-B2 Polycarbonates and polybutylene terephthalate; impact resistance TORAY INDUSTRIES, INC. (JP) 2008-06-10 US disclosed
US-20060142423-A1 Polybutylene terephthalate resin composition for vibration welding WINTECH POLYMER LTD. (JP) 2006-06-29 US disclosed
US-20060079638-A1 Polybutylene terephthalate resin composition WINTECH POLYMER LTD. (JP) 2006-04-13 US disclosed
US-20050256275-A1 Polycarbonates and polybutylene terephthalate; impact resistance TORAY INDUSTRIES, INC. (JP) 2005-11-17 US disclosed
EP-1595920-A1 Polymer alloy, thermoplastic resin composition, and molded article TORAY INDUSTRIES, INC. (JP) 2005-11-16 EP disclosed
US-20040071908-A1 Fuel hose TOKAI RUBBER INDUSTRIES, LTD. (JP) 2004-04-15 US disclosed
US-6512027-B2 Thermoplastic resin with 1-25% by weight of an impact resistance giving agent, 1-50% by weight of an inorganic filler and .1-10% by weight of an aromatic polyvalent carboxylate; molding material POLYPLASTICS CO., LTD. (JP) 2003-01-28 US disclosed
US-6447913-B1 RESISTANT TO ALKALINE SOLUTIONS FOR A LONG TIME, LOW STRESS, MOLDINGS; BLEND WITH IMPACT RESISTANCE MATERIAL, A SILICONE AND/OR FLUOROPOLYMER, INORGANIC FILLER, AND A POLYFUNCTIONAL EPOXY, ISOCYANATE, OR DIANHYDRIDE COMPOUND POLYPLASTICS CO., LTD (JP) 2002-09-10 US disclosed
US-20020077399-A1 Polyester resin composition POLYPLASTICS CO., LTD. (JP) 2002-06-20 US disclosed
US-6180251-B1 INPACT RESISTANCE AGENT; INORGANIC FILLER; FLAME RETARDANT; AROMATIC POLYVALENT CARBOXYLATE SUCH AS A TRIMELLITATE OR PYROMELLITATE POLYPLASTICS CO. LTD. (JP) 2001-01-30 US disclosed