SCHEMBL23748538

SCHEMBL23748538

CC1(C)O[Si](c2ccccc2)(c2ccccc2)CCC1(C)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
OPRM1 P35372 4/20 0.32
OPRL1 P41146 3/20 0.32
OPRK1 P41145 2/20 0.32
DRD4 P21917 1/20 0.32
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
PAX8 Q06710 1/20 0.31
MCL1 Q07820 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
AKR1C1 Q04828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27962277 0.81 DRD4 (0.31) OPRM1DRD4
SCHEMBL6573456 0.79 TSHR (0.35) TSHROPRM1OPRL1OPRK1DRD4
SCHEMBL2048192 0.78 OPRM1 (0.36) OPRM1OPRL1OPRK1DRD4ALDH1A1
SCHEMBL2232615 0.77 OPRM1 (0.35) OPRM1OPRL1OPRK1DRD4ALDH1A1
SCHEMBL28269509 0.76
SCHEMBL2369738 0.74
SCHEMBL182249 0.70
SCHEMBL28711657 0.70 AKR1C1 (0.30) AKR1C1
Ammonia Solution, Strong SCHEMBL7586755 0.69
SCHEMBL2352430 0.69 AKR1C1 (0.35) AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3863593-A1 PROCESS FOR TREATING KERATIN FIBERS EMPLOYING AN ANHYDRIDE ACRYLIC POLYMER IN OILY DISPERSION AND AN AMINE COMPOUND L'OREAL (FR) 2021-08-18 EP disclosed