SCHEMBL2232615

SCHEMBL2232615

CC1(C)CC[Si](c2ccccc2)(c2ccccc2)OC1(c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 4/20 0.35
DRD4 P21917 1/20 0.35
OPRK1 P41145 2/20 0.32
OPRL1 P41146 1/20 0.32
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
PAX8 Q06710 1/20 0.31
MCL1 Q07820 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
SLC22A1 O15245 1/20 0.31
SLC6A4 P31645 1/20 0.31
ADRA1A P35348 1/20 0.31
OPRD1 P41143 1/20 0.31
KCNH2 Q12809 1/20 0.31
AKR1C1 Q04828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2048192 0.85 OPRM1 (0.36) OPRM1DRD4OPRK1OPRL1ALDH1A1
SCHEMBL27962277 0.81 DRD4 (0.31) OPRM1DRD4
SCHEMBL28711657 0.80 AKR1C1 (0.30) AKR1C1
SCHEMBL23748538 0.77 TSHR (0.33) OPRM1DRD4OPRK1OPRL1ALDH1A1
SCHEMBL1289085 0.77 ICMT (0.31) ALDH1A1LMNAGAAPAX8MCL1
SCHEMBL1055776 0.76 TET3 (0.30)
SCHEMBL6839562 0.75 ICMT (0.31) ALDH1A1LMNAGAAPAX8MCL1
SCHEMBL5488956 0.74 OPRM1 (0.31) OPRM1DRD4OPRK1OPRL1
SCHEMBL28026738 0.74 DRD4 (0.30) OPRM1DRD4
SCHEMBL27605394 0.73 OPRM1 (0.30) OPRM1OPRK1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110003471-B Polysiloxane compound with main chain containing phenylene group and phenylene ether group and preparation method thereof 湖北航聚科技有限公司 2021-08-13 CN claimed
EP-2419079-B1 COMPOSITION COMPRISING SILICONE OIL OR OILS STRUCTURED WITH COPOLYMERS CARRYING GREATER THAN 70% LONG CHAIN ALKYL GROUP UNILEVER PLC NO 41424 (GB) 2017-10-04 EP claimed
WO-2024106312-A1 COSMETIC HAVING CROSSLINKED ORGANOSILOXANE POLYMER 信越化学工業株式会社 2024-05-23 WO disclosed
CN-115011304-A Optical bonding pouring sealant and preparation method thereof 惠州市华利新材料有限公司 2022-09-06 CN disclosed
US-20150368824-A1 WATER AND OIL ULTRA-REPELLENT STRUCTURE AND MANUFACTURING METHOD THEREFOR KOOKMIN UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION (KR) 2015-12-24 US disclosed
WO-2014110511-A1 PROTECTIVE BARRIERS FOR PREVENTING OR REDUCING TRANSFER OF MICROORGANISMS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2014-07-17 WO disclosed
US-20130059113-A1 Structures For Preventing Microorganism Attachment PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2013-03-07 US disclosed
EP-2528635-A1 STRUCTURES FOR PREVENTING MICROORGANISM ATTACHMENT President and Fellows of Harvard College (US) 2012-12-05 EP disclosed
US-8202614-B2 Additive particles having superhydrophobic characteristics and coatings and methods of making and using the same LUNA INNOVATIONS INCORPORATED (US) 2012-06-19 US disclosed
WO-2011094344-A1 STRUCTURES FOR PREVENTING MICROORGANISM ATTACHMENT PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2011-08-04 WO disclosed
US-20090298369-A1 ADDITIVE PARTICLES HAVING SUPERHYDROPHOBIC CHARACTERISTICS AND COATINGS AND METHODS OF MAKING AND USING THE SAME LUNA INNOVATIONS INCORPORATED (US) 2009-12-03 US disclosed
US-7344783-B2 Durable hydrophobic surface coatings using silicone resins SHELL OIL COMPANY (US) 2008-03-18 US disclosed
EP-1660601-A1 DURABLE HYDROPHOBIC SURFACE COATINGS USING SILICONE RESINS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 2006-05-31 EP disclosed
EP-1523455-A1 HYDROPHOBIC SURFACE TREATMENT COMPOSITION AND METHOD OF MAKING AND USING SAME SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2005-04-20 EP disclosed
WO-2005007764-A1 DURABLE HYDROPHOBIC SURFACE COATINGS USING SILICONE RESINS SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2005-01-27 WO disclosed
US-20050009953-A1 Durable hydrophobic surface coatings using silicone resins PENNZOIL-QUAKER STATE COMPANY 2005-01-13 US disclosed
US-20040202872-A1 Hydrophobic surface treatment composition and method of making and using same PENNZOIL-QUAKER STATE COMPANY 2004-10-14 US disclosed
WO-2004009505-A1 HYDROPHOBIC SURFACE TREATMENT COMPOSITION AND METHOD OF MAKING AND USING SAME SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2004-01-29 WO disclosed
US-5415927-A Water-repellant glass products and process for the production thereof NIPPON SHEET GLASS CO., LTD. (JP) 1995-05-16 US disclosed