SCHEMBL20482123

SCHEMBL20482123

Cc1nc2cc(C(C)N3CCN(c4ccc([S+](C)[O-])cc4)CC3)ccc2s1

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
OGA O60502 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25901885 0.86 OGA (0.66) OGA
SCHEMBL25901904 0.86 OGA (0.68) OGA
SCHEMBL20482016 0.83 OGA (0.56) OGA
SCHEMBL21764478 0.82 OGA (0.75) OGA
SCHEMBL20482182 0.82 OGA (0.70) OGA
SCHEMBL25682701 0.78 OGA (0.60) OGA
SCHEMBL21604866 0.78 OGA (0.59) OGA
SCHEMBL25682831 0.77 OGA (0.71) OGA
SCHEMBL24499335 0.76 OGA (0.76) OGA
SCHEMBL23575845 0.75 OGA (0.60) OGA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250115604-A1 SULFOXIMINE GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2025-04-10 US disclosed
US-12195455-B2 Succinate and fumarate acid addition salts of piperazine derivatives ASCENEURON SA (CH) 2025-01-14 US disclosed
US-12157734-B2 Sulfoximine glycosidase inhibitors ASCENEURON SA (CH) 2024-12-03 US disclosed
CN-110770226-B Sulfoximine glycosidase inhibitors 阿森纽荣股份公司 2023-11-10 CN disclosed
EP-3841093-B1 SUCCINATE AND FUMARATE ACID ADDITION SALTS OF PIPERAZINE DERIVATIVES USEFUL AS GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2023-06-21 EP disclosed
EP-3841093-B1 SUCCINATE AND FUMARATE ACID ADDITION SALTS OF PIPERAZINE DERIVATIVES USEFUL AS GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2023-06-21 EP disclosed
US-20220177470-A1 SULFOXIMINE GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2022-06-09 US disclosed
US-20220177470-A1 SULFOXIMINE GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2022-06-09 US disclosed
US-11261183-B2 Sulfoximine glycosidase inhibitors ASCENEURON SA (CH) 2022-03-01 US disclosed
CN-113166083-A Succinate and fumarate acid addition salts of piperazine derivatives as glycosidase inhibitors 阿森纽荣股份公司 2021-07-23 CN disclosed
US-20210198250-A1 SUCCINATE AND FUMARATE ACID ADDITION SALTS OF PIPERAZINE DERIVATIVES ASCENEURON SA (CH) 2021-07-01 US disclosed
US-20210198250-A1 SUCCINATE AND FUMARATE ACID ADDITION SALTS OF PIPERAZINE DERIVATIVES ASCENEURON SA (CH) 2021-07-01 US disclosed
EP-3841093-A1 SUCCINATE AND FUMARATE ACID ADDITION SALTS OF PIPERAZINE DERIVATIVES USEFUL AS GLYCOSIDASE INHIBITORS Asceneuron SA (CH) 2021-06-30 EP disclosed
WO-2020039030-A1 SUCCINATE AND FUMARATE ACID ADDITION SALTS OF PIPERAZINE DERIVATIVES USEFUL AS GLYCOSIDASE INHIBITORS ASCENEURON S. A. (CH) 2020-02-27 WO disclosed
WO-2020039030-A1 SUCCINATE AND FUMARATE ACID ADDITION SALTS OF PIPERAZINE DERIVATIVES USEFUL AS GLYCOSIDASE INHIBITORS ASCENEURON S. A. (CH) 2020-02-27 WO disclosed
CN-110770226-A Sulfoximine glycosidase inhibitors 阿森纽荣股份公司 2020-02-07 CN disclosed
WO-2018153508-A2 SULFOXIMINE GLYCOSIDASE INHIBITORS Asceneuron S.A. (CH) 2018-08-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12157734-B2 Sulfoximine glycosidase inhibitors ENGASE, BACE1, GAA OGA 57/4885
US-12195455-B2 Succinate and fumarate acid addition salts of piperazine derivatives FH, SDHA, SDHB OGA 471/4885
US-20220177470-A1 SULFOXIMINE GLYCOSIDASE INHIBITORS ENGASE, BACE1, GAA OGA 57/4885
US-20250115604-A1 SULFOXIMINE GLYCOSIDASE INHIBITORS ENGASE, BACE1, GAA OGA 42/4885
US-20210198250-A1 SUCCINATE AND FUMARATE ACID ADDITION SALTS OF PIPERAZINE DERIVATIVES SDHA, SDHB, SORD OGA 614/4885
US-11261183-B2 Sulfoximine glycosidase inhibitors ENGASE, BACE1, GAA OGA 57/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.