Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | FDPS | P14324 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.54 |
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | HPGD | P15428 | 8/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14036000 | 0.86 | LMNA (0.56) | LMNAFDPSALDH1A1MAPTHPGD | |
| SCHEMBL31471656 | 0.84 | LMNA (0.54) | LMNAFDPSALDH1A1MAPTHPGD | |
| SCHEMBL25781297 | 0.83 | LMNA (0.54) | LMNAFDPSALDH1A1MAPTHPGD | |
| SCHEMBL22160259 | 0.83 | FDPS (0.57) | LMNAFDPSALDH1A1MAPTHPGD | |
| SCHEMBL218012 | 0.83 | FDPS (0.71) | LMNAFDPSALDH1A1MAPTHPGD | |
| SCHEMBL12525838 | 0.81 | FDPS (0.55) | LMNAFDPSALDH1A1MAPTHPGD | |
| SCHEMBL1098158 | 0.81 | ALDH1A1 (0.67) | LMNAFDPSALDH1A1MAPTHPGD | |
| SCHEMBL11686330 | 0.81 | LMNA (0.54) | LMNAFDPSALDH1A1MAPTHPGD | |
| SCHEMBL30694794 | 0.81 | LMNA (0.54) | LMNAFDPSALDH1A1MAPTHPGD | |
| SCHEMBL3569232 | 0.81 | LMNA (0.54) | LMNAFDPSALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018154466-A1 | DIHYDROQUINOLIZINONES AS ANTIVIRALS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-08-30 | — | — | WO | disclosed |