Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 16/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20482549 | 0.83 | REN (0.44) | RENALDH1A1 | |
| SCHEMBL20482570 | 0.80 | REN (0.41) | REN | |
| SCHEMBL20482799 | 0.79 | REN (0.39) | REN | |
| SCHEMBL20482637 | 0.78 | KMT2A (0.48) | RENALDH1A1 | |
| SCHEMBL20482672 | 0.78 | REN (0.46) | RENALDH1A1SMPD1 | |
| SCHEMBL20482612 | 0.78 | KDM4E (0.36) | RENALDH1A1 | |
| SCHEMBL20482537 | 0.77 | REN (0.43) | RENALDH1A1 | |
| SCHEMBL20482664 | 0.76 | REN (0.45) | REN | |
| SCHEMBL20482253 | 0.73 | SMPD1 (0.52) | ALDH1A1SMPD1 | |
| SCHEMBL17709374 | 0.73 | REN (0.49) | RENALDH1A1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018154466-A1 | DIHYDROQUINOLIZINONES AS ANTIVIRALS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-08-30 | — | — | WO | disclosed |