Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20482885 | 0.84 | KMT2A (0.48) | ALDH1A1KMT2AGAAKDM4EMEN1 | |
| SCHEMBL20482446 | 0.84 | TSHR (0.38) | ALDH1A1KMT2ACASP1GAATSHR | |
| SCHEMBL20482240 | 0.82 | REN (0.41) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL20482850 | 0.80 | ALDH1A1 (0.51) | ALDH1A1CA2KMT2ACASP1POLB | |
| SCHEMBL20482372 | 0.79 | REN (0.40) | KMT2AMEN1 | |
| SCHEMBL20482792 | 0.78 | REN (0.40) | KMT2ATSHR | |
| SCHEMBL20483174 | 0.77 | SLC6A4 (0.36) | ALDH1A1KMT2APOLBKDM4EMEN1 | |
| SCHEMBL21496002 | 0.71 | ATM (0.50) | ALDH1A1CA2KMT2ACASP1GAA | |
| SCHEMBL20482392 | 0.71 | ALDH1A1 (0.51) | ALDH1A1CA2KMT2ACASP1GAA | |
| Hydrochloric Acid SCHEMBL21496001 | 0.70 | CASP1 (0.49) | ALDH1A1CA2KMT2ACASP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018154466-A1 | DIHYDROQUINOLIZINONES AS ANTIVIRALS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-08-30 | — | — | WO | disclosed |