Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | MPL | P40238 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14721068 | 0.87 | ALDH1A1 (0.33) | ALDH1A1GAAMEP1BMEN1KMT2A | |
| SCHEMBL30278562 | 0.86 | ALDH1A1 (0.36) | ALDH1A1GAAMEP1BMEN1KMT2A | |
| SCHEMBL776513 | 0.86 | ALDH1A1 (0.36) | ALDH1A1GAAMEP1BMEN1KMT2A | |
| SCHEMBL31544811 | 0.86 | ALDH1A1 (0.36) | ALDH1A1GAAMEP1BMEN1KMT2A | |
| SCHEMBL242277 | 0.83 | TAAR1 (0.38) | ALDH1A1GAAMEP1BMEN1KMT2A | |
| SCHEMBL30439901 | 0.83 | MPL (0.36) | ALDH1A1GAAMEP1BMEN1KMT2A | |
| SCHEMBL30439756 | 0.83 | ALDH1A1 (0.35) | ALDH1A1GAAMEP1BMEN1KMT2A | |
| SCHEMBL1607815 | 0.82 | RAPGEF4 (0.44) | ALDH1A1GAAMEP1BMEN1KMT2A | |
| SCHEMBL30236538 | 0.82 | RAPGEF4 (0.44) | ALDH1A1GAAMEP1BMEN1KMT2A | |
| SCHEMBL1180196 | 0.82 | GAA (0.41) | ALDH1A1GAAMEP1BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025464-A1 | FLUORODEUTERIOMETHYL TYROSINE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-01 | — | — | WO | disclosed |