Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | MPL | P40238 | 1/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30439756 | 0.93 | ALDH1A1 (0.35) | ALDH1A1GAAMEP1BMEN1KMT2A | |
| SCHEMBL30439901 | 0.93 | MPL (0.36) | ALDH1A1GAAMEP1BMEN1KMT2A | |
| SCHEMBL14721068 | 0.90 | ALDH1A1 (0.33) | ALDH1A1GAAMEP1BMEN1KMT2A | |
| SCHEMBL31544811 | 0.89 | ALDH1A1 (0.36) | ALDH1A1GAAMEP1BMEN1KMT2A | |
| SCHEMBL31674524 | 0.89 | MYC (0.35) | ALDH1A1GAAMEP1BMEN1KMT2A | |
| SCHEMBL20485 | 0.86 | ALDH1A1 (0.35) | ALDH1A1GAAMEP1BMEN1KMT2A | |
| SCHEMBL1607815 | 0.85 | RAPGEF4 (0.44) | ALDH1A1GAAMEP1BMEN1KMT2A | |
| SCHEMBL30823619 | 0.85 | GAA (0.41) | ALDH1A1GAAMEP1BMEN1KMT2A | |
| SCHEMBL1180196 | 0.85 | GAA (0.41) | ALDH1A1GAAMEP1BMEN1KMT2A | |
| SCHEMBL30716894 | 0.85 | AMY1A (0.44) | ALDH1A1GAAMEP1BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12454536-B2 | Deuterated 7-(3-(4-(2-([18F]fluoro)ethoxy)phenyl)propyl)-2-(furan-2-yl)-7H- pyrazolo [4,3-e][1,2,4]triazolo[1,5-C]pyrimidine-5-amine derivatives | HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF E.V. (DE) | 2025-10-28 | — | — | US | disclosed |
| US-20230095104-A1 | DEUTERATED 7-(3-(4-(2-([18F]FLUOR)ETHOXY)PHENYL)PROPYL)-2-(FURAN-2-YL)-7HPYRAZOLO [4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE DERIVATIVES | HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF E.V. (DE) | 2023-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230095104-A1 | DEUTERATED 7-(3-(4-(2-([18F]FLUOR)ETHOXY)PHENYL)PROPYL)-2-(FURAN-2-YL)-7HPYRAZOLO [4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE DERIVATIVES | XDH, XPO4, FPR3 | ALDH1A1 3778/4885GAA 2646/4885MEP1B 837/4885 |
| US-12454536-B2 | Deuterated 7-(3-(4-(2-([18F]fluoro)ethoxy)phenyl)propyl)-2-(furan-2-yl)-7H- pyrazolo [4,3-e][1,2,4]triazolo[1,5-C]pyrimidine-5-amine derivatives | XDH, XPO4, XPO5 | ALDH1A1 3561/4885GAA 3498/4885MEP1B 850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.