Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL600327 | 0.90 | TAAR1 (0.36) | TAAR1GAAHSD17B10AMY1AMEP1B | |
| SCHEMBL30823619 | 0.89 | GAA (0.41) | TAAR1GAAHSD17B10AMY1AMEP1B | |
| SCHEMBL1180196 | 0.89 | GAA (0.41) | TAAR1GAAHSD17B10AMY1AMEP1B | |
| SCHEMBL8496556 | 0.87 | TAAR1 (0.34) | TAAR1GAAHSD17B10AMY1AMEP1B | |
| SCHEMBL6968755 | 0.87 | TAAR1 (0.34) | TAAR1GAAHSD17B10AMY1AMEP1B | |
| SCHEMBL9562138 | 0.87 | TAAR1 (0.34) | TAAR1GAAHSD17B10AMY1AMEP1B | |
| SCHEMBL3975257 | 0.86 | TAAR1 (0.55) | TAAR1GAAHSD17B10AMY1AMEP1B | |
| SCHEMBL5718625 | 0.86 | GAA (0.39) | TAAR1GAAHSD17B10AMY1AMEP1B | |
| SCHEMBL816601 | 0.86 | GAA (0.39) | TAAR1GAAHSD17B10AMY1AMEP1B | |
| SCHEMBL30723203 | 0.86 | GAA (0.39) | TAAR1GAAHSD17B10AMY1AMEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11242314-B2 | Synthesizing pet tracers using [F-18]sulfonyl fluoride as a source of [F-18]fluoride | WASHINGTON UNIVERSITY (US) | 2022-02-08 | — | — | US | claimed |
| US-20170197912-A1 | SYNTHESIZING PET TRACERS USING [F-18]SULFONYL FLUORIDE AS A SOURCE OF [F-18]FLUORIDE | WASHINGTON UNIVERSITY (US) | 2017-07-13 | — | — | US | claimed |
| WO-2008132211-A1 | AMINO-QUINAZOLINONE DERIVATIVES FOR USE AS RADIOTRACERS AND IMAGING AGENTS | NOVARTIS AG (CH) | 2008-11-06 | — | — | WO | claimed |
| EP-0195135-B1 | A PROCESS FOR THE PREPARATION OF QUINOLINE CARBOXYLIC ACID DERIVATIVES | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1992-06-17 | — | — | EP | claimed |
| US-20250388523-A1 | 18F-LABELED PEPTIDE LIGANDS USEFUL IN PET AND CERENKOV LUMINESCENE IMAGING | CORNELL UNIVERSITY (US) | 2025-12-25 | — | — | US | disclosed |
| US-12297157-B2 | 18F-labeled peptide ligands useful in PET and Cerenkov luminescene imaging | CORNELL UNIVERSITY (US) | 2025-05-13 | — | — | US | disclosed |
| WO-2025085387-A1 | SUBSTITUTED-ALKENYL-INDAZOLES FOR IMAGING AGGREGATED TAU IN TAUOPATHIES | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2025-04-24 | — | — | WO | disclosed |
| WO-2025074096-A1 | P97 (VCP) ATPASE INHIBITORS | Turbine Simulated Cell Technologies Ltd (GB) | 2025-04-10 | — | — | WO | disclosed |
| US-20240409499-A1 | VOLTAGE GATED SODIUM CHANNEL IMAGING AGENTS | MASSACHUSETTS GEN HOSPITAL (US) | 2024-12-12 | — | — | US | disclosed |
| US-12006302-B2 | Tau PET imaging ligands | JANSSEN PHARMACEUTICA NV (BE) | 2024-06-11 | — | — | US | disclosed |
| CN-117624166-A | Triazole derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-03-01 | — | — | CN | disclosed |
| WO-2024042147-A2 | NOVEL DEUTERATED PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-29 | — | — | WO | disclosed |
| US-20080070894-A1 | Novel Substituted Imidazole Derivative | MSD K.K. (JP) | 2008-03-20 | — | — | US | disclosed |
| EP-1896400-A1 | IMAGING 18F OR 11C-LABELLED ALKYLTHIOPHENYL GUANIDINES | Hammersmith Imanet, Ltd (GB) | 2008-03-12 | — | — | EP | disclosed |
| EP-1790650-A1 | NOVEL SUBSTITUTED IMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-05-30 | — | — | EP | disclosed |
| WO-2007057705-A1 | TETRACYCLIC INDOLE DERIVATIVES AS IN VIVO IMAGING AGENTS AND HAVING PERIPHERALBENZODIAZEPINE RECEPTOR AFFINITY (PBR) | HAMMERSMITH IMANET LIMITED (GB) | 2007-05-24 | — | — | WO | disclosed |
| WO-2006136846-A1 | IMAGING 18F OR 11C-LABELLED ALKYLTHIOPHENYL GUANIDINES | HAMMERSMITH IMANET LIMITED (GB) | 2006-12-28 | — | — | WO | disclosed |
| EP-1718635-A1 | PIPERIDINYL TARGETING COMPOUNDS THAT SELECTIVELY BIND INTEGRINS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005082889-A1 | PIPERIDINYL TARGETING COMPOUNDS THAT SELECTIVELY BIND INTEGRINS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-09-09 | — | — | WO | disclosed |
| US-20040224986-A1 | Piperidinyl targeting compounds that selectively bind integrins | JANSSEN PHARMACEUTICA, NV (BE) | 2004-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170197912-A1 | SYNTHESIZING PET TRACERS USING [F-18]SULFONYL FLUORIDE AS A SOURCE OF [F-18]FLUORIDE | STX18, GPR119, SLC5A1 | TAAR1 3098/4885GAA 268/4885HSD17B10 4288/4885 |
| US-20080070894-A1 | Novel Substituted Imidazole Derivative | PLK1, CDK1, CDK11A | TAAR1 3791/4885GAA 4379/4885HSD17B10 3515/4885 |
| US-11242314-B2 | Synthesizing pet tracers using [F-18]sulfonyl fluoride as a source of [F-18]fluoride | STX18, GPR119, SLC5A1 | TAAR1 3098/4885GAA 268/4885HSD17B10 4288/4885 |
| US-20240409499-A1 | VOLTAGE GATED SODIUM CHANNEL IMAGING AGENTS | CACNA1B, CACNA1G, CACNA1I | TAAR1 1078/4885GAA 3137/4885HSD17B10 3097/4885 |
| US-20250388523-A1 | 18F-LABELED PEPTIDE LIGANDS USEFUL IN PET AND CERENKOV LUMINESCENE IMAGING | SCTR, SSTR3, SSTR1 | TAAR1 208/4885GAA 3348/4885HSD17B10 4621/4885 |
| US-12006302-B2 | Tau PET imaging ligands | MAPT, PSEN1, APP | TAAR1 634/4885GAA 661/4885HSD17B10 4217/4885 |
| US-12297157-B2 | 18F-labeled peptide ligands useful in PET and Cerenkov luminescene imaging | VIP, CALCA, GLP1R | TAAR1 1415/4885GAA 587/4885HSD17B10 4262/4885 |
| US-20040224986-A1 | Piperidinyl targeting compounds that selectively bind integrins | ITGA5, ITGB5, ITGB1 | TAAR1 2540/4885GAA 3078/4885HSD17B10 4866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.