Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL453506 | 0.80 | KDM4E (0.48) | ALOX15KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL7637229 | 0.74 | ALOX15 (0.43) | ALOX15KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL8776626 | 0.74 | ALOX15 (0.43) | ALOX15KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL20605668 | 0.74 | ALOX15 (0.43) | ALOX15KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL454022 | 0.74 | ALDH1A1 (0.47) | ALOX15KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL170101 | 0.74 | ALOX15 (0.43) | ALOX15KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL15348468 | 0.74 | HPGD (0.43) | ALOX15KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL2387037 | 0.74 | AKT2 (0.44) | ALOX15KDM4EALDH1A1HPGDNPC1 | |
| Ammonia Solution, Strong SCHEMBL28924316 | 0.72 | ALOX15 (0.41) | ALOX15KDM4EALDH1A1HPGDNPC1 | |
| Phenol SCHEMBL28258861 | 0.72 | RPS6KA3 (0.45) | KDM4EALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137483-A1 | RHO-ASSOCIATED PROTEIN KINASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2025-06-26 | — | — | WO | disclosed |
| CN-110105355-B | Preparation method of 1,2, 3-triazole- [1,5-a ] quinoline compound | 烟台大学 | 2021-09-21 | — | — | CN | disclosed |
| CN-110105355-A | A kind of preparation method of 1,2,3- triazole-[1,5-a] and quinolines | 烟台大学 | 2019-08-09 | — | — | CN | disclosed |
| EP-2509638-B1 | IODINE RADIOLABELLING METHOD | GE HEALTHCARE LTD (GB) | 2017-04-19 | — | — | EP | disclosed |
| US-20160022846-A1 | IODINE RADIOLABELLING METHOD | GE HEALTHCARE LTD (GB) | 2016-01-28 | — | — | US | disclosed |
| US-8927736-B2 | Copper catalyzed cycloaddition of organic azides and 1-haloalkynes | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-01-06 | — | — | US | disclosed |
| US-8894971-B2 | Iodine radiolabelling method | GE HEALTHCARE LIMITED (GB) | 2014-11-25 | — | — | US | disclosed |
| CN-102770163-A | Iodine radiolabelling method | GE HEALTHCARE LTD | 2012-11-07 | — | — | CN | disclosed |
| EP-2509638-A1 | IODINE RADIOLABELLING METHOD | GE Healthcare UK Limited (GB) | 2012-10-17 | — | — | EP | disclosed |
| US-20120237444-A1 | IODINE RADIOLABELLING METHOD | GE HEALTHCARE LIMITED (GB) | 2012-09-20 | — | — | US | disclosed |
| US-20120142935-A1 | COPPER CATALYZED CYCLOADDITION OF ORGANIC AZIDES AND 1-HALOALKYNES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-06-07 | — | — | US | disclosed |
| WO-2011070136-A1 | IODINE RADIOLABELLING METHOD | GE HEALTHCARE LIMITED (GB) | 2011-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142935-A1 | COPPER CATALYZED CYCLOADDITION OF ORGANIC AZIDES AND 1-HALOALKYNES | AOC3, AOC2, CBR3 | ALOX15 177/4885KDM4E 4198/4885ALDH1A1 223/4885 |
| US-20160022846-A1 | IODINE RADIOLABELLING METHOD | BTD, BTN3A1, BTF3 | ALOX15 4061/4885KDM4E 3901/4885ALDH1A1 3531/4885 |
| US-20120237444-A1 | IODINE RADIOLABELLING METHOD | BTD, BTN3A1, BTF3 | ALOX15 4061/4885KDM4E 3901/4885ALDH1A1 3531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.