Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 2/20 | 0.43 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7622170 | 0.79 | PLA2G10 (0.47) | PLA2G10PLA2G5ACEF2F10 | |
| SCHEMBL7622174 | 0.79 | PLA2G10 (0.47) | PLA2G10PLA2G5ACEF2F10 | |
| SCHEMBL7617920 | 0.77 | PLA2G10 (0.46) | PLA2G10PLA2G5ACEF2F10 | |
| SCHEMBL7617915 | 0.77 | PLA2G10 (0.46) | PLA2G10PLA2G5ACEF2F10 | |
| SCHEMBL20481291 | 0.75 | POLB (0.42) | PLA2G10PLA2G5 | |
| SCHEMBL7619656 | 0.73 | PLA2G10 (0.43) | PLA2G10PLA2G5ACEKDM4E | |
| SCHEMBL7619661 | 0.73 | PLA2G10 (0.43) | PLA2G10PLA2G5ACEKDM4E | |
| SCHEMBL10954499 | 0.71 | PLA2G10 (0.43) | PLA2G10PLA2G5ACEF2F10 | |
| SCHEMBL10691419 | 0.71 | PLA2G10 (0.43) | PLA2G10PLA2G5ACEF2F10 | |
| SCHEMBL6282329 | 0.71 | PLA2G10 (0.47) | PLA2G10PLA2G5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018160521-A2 | INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN | Lazuli, Inc. (US) | 2018-09-07 | — | — | WO | disclosed |