Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 2/20 | 0.47 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7622170 | 1.00 | PLA2G10 (0.47) | PLA2G10PLA2G5ACEF2F10 | |
| SCHEMBL7617915 | 0.83 | PLA2G10 (0.46) | PLA2G10PLA2G5ACEF2F10 | |
| SCHEMBL7617920 | 0.83 | PLA2G10 (0.46) | PLA2G10PLA2G5ACEF2F10 | |
| SCHEMBL20488361 | 0.79 | PLA2G10 (0.43) | PLA2G10PLA2G5ACEF2F10 | |
| SCHEMBL7619656 | 0.79 | PLA2G10 (0.43) | PLA2G10PLA2G5ACEKDM4EALDH1A1 | |
| SCHEMBL7619661 | 0.79 | PLA2G10 (0.43) | PLA2G10PLA2G5ACEKDM4EALDH1A1 | |
| SCHEMBL10691419 | 0.77 | PLA2G10 (0.43) | PLA2G10PLA2G5ACEF2F10 | |
| SCHEMBL10954499 | 0.77 | PLA2G10 (0.43) | PLA2G10PLA2G5ACEF2F10 | |
| SCHEMBL6282329 | 0.76 | PLA2G10 (0.47) | PLA2G10PLA2G5KDM4EALDH1A1SCN9A | |
| SCHEMBL10914619 | 0.76 | PLA2G10 (0.43) | PLA2G10PLA2G5ACEF2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620225-B1 | Cephalosporin derivatives | BASILEA PHARMACEUTICA AG (CH) | 2002-11-13 | — | — | EP | disclosed |
| US-5523400-A | 3-(PYRROLIDIN-3-YLIDENE=CH-),7-((2-AMINOTHIAZOL-4-YL)HYDROX -IMINOACETYLAMINO-)-3-CEPHEM DERIVATIVES; BROAD SPECTRUM ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1996-06-04 | — | — | US | disclosed |
| EP-0620225-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1994-10-19 | — | — | EP | disclosed |