Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 2/20 | 0.43 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.43 |
| ▸ | STS | P08842 | 2/20 | 0.33 |
| ▸ | ACE | P12821 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7619661 | 1.00 | PLA2G10 (0.43) | PLA2G10PLA2G5STSACEGPR119 | |
| SCHEMBL7622174 | 0.79 | PLA2G10 (0.47) | PLA2G10PLA2G5ACEKDM4EALDH1A1 | |
| SCHEMBL7622170 | 0.79 | PLA2G10 (0.47) | PLA2G10PLA2G5ACEKDM4EALDH1A1 | |
| SCHEMBL7617920 | 0.77 | PLA2G10 (0.46) | PLA2G10PLA2G5ACEKDM4EALDH1A1 | |
| SCHEMBL7617915 | 0.77 | PLA2G10 (0.46) | PLA2G10PLA2G5ACEKDM4EALDH1A1 | |
| SCHEMBL21519313 | 0.73 | HRH3 (0.36) | PLA2G10PLA2G5GPR119 | |
| SCHEMBL20488361 | 0.73 | PLA2G10 (0.43) | PLA2G10PLA2G5ACEKDM4E | |
| SCHEMBL10954499 | 0.71 | PLA2G10 (0.43) | PLA2G10PLA2G5ACE | |
| SCHEMBL10691419 | 0.71 | PLA2G10 (0.43) | PLA2G10PLA2G5ACE | |
| SCHEMBL6282329 | 0.71 | PLA2G10 (0.47) | PLA2G10PLA2G5KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620225-B1 | Cephalosporin derivatives | BASILEA PHARMACEUTICA AG (CH) | 2002-11-13 | — | — | EP | disclosed |
| US-5523400-A | 3-(PYRROLIDIN-3-YLIDENE=CH-),7-((2-AMINOTHIAZOL-4-YL)HYDROX -IMINOACETYLAMINO-)-3-CEPHEM DERIVATIVES; BROAD SPECTRUM ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1996-06-04 | — | — | US | disclosed |
| EP-0620225-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1994-10-19 | — | — | EP | disclosed |