⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alpha-Ketoglutaric Acid SCHEMBL1261453 | 0.83 | EGLN1 (0.74) | — | |
| SCHEMBL728986 | 0.81 | — | — | |
| SCHEMBL728991 | 0.79 | NFKB1 (0.62) | — | |
| Hydrochloric Acid SCHEMBL28408226 | 0.79 | BLM (0.57) | — | |
| SCHEMBL1673131 | 0.79 | OR51E2 (0.40) | — | |
| SCHEMBL361798 | 0.78 | OR51E2 (0.79) | — | |
| SCHEMBL28754323 | 0.77 | OR51E2 (0.44) | — | |
| SCHEMBL285020 | 0.77 | LMNA (0.64) | — | |
| SCHEMBL2368877 | 0.77 | LMNA (0.64) | — | |
| SCHEMBL16585547 | 0.77 | HAO1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115666653-A | Antibody-drug conjugates | 斯皮雷亚有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-103896940-B | A kind of synthetic method of Eliquis | CHEMFUTURE PHARMATECH (JIANGSU), LTD. (CN) | 2016-02-03 | — | — | CN | claimed |
| CN-103896940-A | Synthetic method of Apixaban | CHEMFUTURE PHARMATECH JIANGSU LTD | 2014-07-02 | — | — | CN | claimed |
| CN-115666653-A | Antibody-drug conjugates | 斯皮雷亚有限公司 | 2023-01-31 | — | — | CN | disclosed |
| US-20220054649-A1 | ANTIBODY-DRUG CONJUGATES | SPIREA LIMITED (GB) | 2022-02-24 | — | — | US | disclosed |
| EP-3897744-A1 | ANTIBODY-DRUG CONJUGATES | Spirea Limited (GB) | 2021-10-27 | — | — | EP | disclosed |
| CN-113226378-A | Antibody-drug conjugates | 斯皮雷亚有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-111171041-B | 20-substituted camptothecin derivative and preparation method and application thereof | 中国海洋大学 | 2021-07-27 | — | — | CN | disclosed |
| WO-2020128488-A1 | ANTIBODY-DRUG CONJUGATES | SPIREA LIMITED (GB) | 2020-06-25 | — | — | WO | disclosed |
| CN-111171041-A | 20-substituted camptothecin derivative and preparation method and application thereof | 中国海洋大学 | 2020-05-19 | — | — | CN | disclosed |
| CN-110003123-A | For treating the PGI2 receptor modulators of prostacyclin (PGI2) receptor associate disorder | 艾尼纳制药公司 | 2019-07-12 | — | — | CN | disclosed |
| WO-2010011998-A1 | ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-01-28 | — | — | WO | disclosed |
| WO-2009085072-A1 | COMPOSITION COMPRISING CHELATING AGENTS CONTAINING AMIDOXIME COMPOUNDS | EKC TECHNOLOGY, INC (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009058274-A1 | CHEMICAL MECHANICAL POLISHING AND WAFER CLEANING COMPOSITION COMPRISING AMIDOXIME COMPOUNDS AND ASSOCIATED METHOD FOR USE | EKC TECHNOLOGY, INC. (US) | 2009-05-07 | — | — | WO | disclosed |
| WO-2009058272-A1 | COPPER CMP POLISHING PAD CLEANING COMPOSITION COMPRISING OF AMIDOXIME COMPOUNDS | EKC TECHNOLOGY, INC. (US) | 2009-05-07 | — | — | WO | disclosed |
| WO-2009058275-A1 | METHODS OF POST CHEMICAL MECHANICAL POLISHING AND WAFER CLEANING USING AMIDOXIME COMPOSITIONS | EKC TECHNOLOGY, INC. (US) | 2009-05-07 | — | — | WO | disclosed |
| WO-2009058278-A1 | METHODS OF CLEANING SEMICONDUCTOR DEVICES AT THE BACK END OF LINE USING AMIDOXIME COMPOSITIONS | EKC TECHNOLOGY, INC (US) | 2009-05-07 | — | — | WO | disclosed |
| WO-2009058288-A1 | AMIDOXIME COMPOUNDS AS CHELATING AGENTS IN SEMICONDUCTOR PROCESSES | EKC TECHNOLOGY, INC. (US) | 2009-05-07 | — | — | WO | disclosed |
| JP-2007106706-A | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO ALCOHOL | TAKASAGO INTERNATL CORP | 2007-04-26 | — | — | JP | disclosed |
| US-4740531-A | REACTION INJECTION MOLDING MATERIALS; LOW VISCOSITY; COMPACT SURFACES | BAYER AKTIENGESELLSCHAFT (DE) | 1988-04-26 | — | — | US | disclosed |