SCHEMBL2049372

SCHEMBL2049372

C=CC(O)c1[c]cccc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1436256 0.75
SCHEMBL11116133 0.75
SCHEMBL8036341 0.75
SCHEMBL5424032 0.75
SCHEMBL827528 0.75
SCHEMBL11258835 0.75
SCHEMBL1960796 0.73 SRC (0.36) TSHR
SCHEMBL3011286 0.72 KDM4E (0.41) ALDH1A1
SCHEMBL16295809 0.72
SCHEMBL9065476 0.72 ALOX15 (0.39) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 682 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190284140-A1 COMPOSITIONS AND METHODS FOR TREATING TUBERCULOSIS THE BROAD INSTITUTE, INC. 2019-09-19 US claimed
CN-110114366-A Two banks quinolone conjugate and application thereof 百奥维骨有限责任公司 2019-08-09 CN claimed
CN-108699044-A New pyrrolidin derivatives 豪夫迈·罗氏有限公司 2018-10-23 CN claimed
US-20180289684-A1 MAPK INHIBITORS EverBrilliant Pharma Pty Ltd (AU) 2018-10-11 US claimed
CN-104871289-B Use of a composition comprising a surfactant and a hydrophobising agent to avoid pattern collapse when processing patterned materials having a line spacing dimension of 50nm or less 巴斯夫欧洲公司 2017-10-10 CN claimed
US-20170266173-A1 MAPK INHIBITORS EVERBRILLIANT PHARMA PTY LTD. (AU) 2017-09-21 US claimed
WO-2017027768-A1 COMPOSITIONS AND METHODS FOR TREATING TUBERCULOSIS THE BROAD INSTITUTE, INC. (US) 2017-02-16 WO claimed
CN-105520941-A Substituted gamma lactams as therapeutic agents ALLERGAN INC 2016-04-27 CN claimed
CN-104871289-A Use of a composition comprising a surfactant and a hydrophobising agent to avoid resistance to pattern collapse when treating patterned materials having a line spacing dimension of 50nm or less BASF SE 2015-08-26 CN claimed
EP-2758383-A1 AROMATIC AMIDOTHIAZOLES, COSMETIC OR DERMATOLOGICAL PREPARATIONS CONTAINING SAID AROMATIC AMIDOTHIAZOLES, AND USE THEREOF TO COMBAT OR PREVENT UNDESIRED PIGMENTATION OF THE SKIN Beiersdorf AG (DE) 2014-07-30 EP claimed
US-20030105164-A1 Solid phase synthesis of arylretinamides NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2003-06-05 US claimed
WO-2003003987-A2 SOLID PHASE SYNTHESIS OF ARYLRETINAMIDES THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2003-01-16 WO claimed
EP-0466319-B1 Hydroxyalkylation of phenols or thiophenols with cyclic organic carbonates using triorganophosphine catalysts INDSPEC CHEMICAL CORP (US) 1998-05-06 EP claimed
US-5059723-A Efficiency; purity INDSPEC CHEMICAL CORPORATION (US) 1991-10-22 US claimed
US-4932473-A ENHANCED OIL RECOVERY SHELL OIL COMPANY (US) 1990-06-12 US claimed
US-4833240-A SKIN DISORDERS; ANTIINFLAMMATORY AGENTS; ANTIALLLERGENS; ANTITUMOR AGENTS; OPHTHALMOLOGY CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD) (FR) 1989-05-23 US claimed
EP-0237075-A2 Prespotter laundry detergent S.C. JOHNSON & SON, INC. (US) 1987-09-16 EP claimed
US-4520095-A STABLE CYAN DYE FOR COLOR DIFFUSION TRANSFER IN SILVER HALIDE EMULSION-CONTAINING FILMS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-05-28 US claimed
US-4122256-A OPTICAL BRIGHTENERS HOECHST AKTIENGESELLSCHAFT (DE) 1978-10-24 US claimed
US-4052433-A INTERMEDIATES FOR BENZOFURANS HOECHST AKTIENGESELLSCHAFT (DT) 1977-10-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190284140-A1 COMPOSITIONS AND METHODS FOR TREATING TUBERCULOSIS C5, IFNG, TERT ALDH1A1 1848/4885TSHR 3335/4885
US-20170266173-A1 MAPK INHIBITORS MAPK1, MAPK4, MAPK3 ALDH1A1 1797/4885TSHR 2701/4885
US-20030105164-A1 Solid phase synthesis of arylretinamides RARA, LRAT, NR2E3 ALDH1A1 1637/4885TSHR 28/4885
US-20180289684-A1 MAPK INHIBITORS MAPK1, MAPK4, MAPK3 ALDH1A1 1797/4885TSHR 2701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.