Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 8/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20580222 | 0.86 | ALDH1A1 (0.46) | KDM4EALDH1A1L3MBTL1PIK3CAMTOR | |
| SCHEMBL18395215 | 0.84 | ALDH1A1 (0.44) | KDM4EALDH1A1L3MBTL1PIK3CAMTOR | |
| SCHEMBL18395121 | 0.83 | ALDH1A1 (0.43) | KDM4EALDH1A1L3MBTL1PIK3CAMTOR | |
| SCHEMBL18395298 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1L3MBTL1PIK3CAMTOR | |
| SCHEMBL18394877 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1L3MBTL1PIK3CAMTOR | |
| SCHEMBL18394620 | 0.77 | ALDH1A1 (0.49) | KDM4EALDH1A1L3MBTL1PIK3CAMTOR | |
| SCHEMBL20867219 | 0.76 | ALDH1A1 (0.51) | KDM4EALDH1A1L3MBTL1PIK3CAMTOR | |
| SCHEMBL18394319 | 0.76 | ALDH1A1 (0.48) | KDM4EALDH1A1L3MBTL1PIK3CAMTOR | |
| SCHEMBL18394751 | 0.75 | KDM4E (0.46) | KDM4EALDH1A1L3MBTL1PIK3CAMTOR | |
| SCHEMBL20098203 | 0.74 | ALDH1A1 (0.47) | KDM4EALDH1A1L3MBTL1PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10570153-B2 | Benzodiazepine derivatives as RSV inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2020-02-25 | — | — | US | disclosed |
| US-20180258102-A1 | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARM INC (US) | 2018-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570153-B2 | Benzodiazepine derivatives as RSV inhibitors | GABRA5, GABRA1, GABBR2 | KDM4E 1198/4885ALDH1A1 621/4885L3MBTL1 4773/4885 |
| US-20180258102-A1 | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | GABRA5, GABRA1, GABBR2 | KDM4E 1198/4885ALDH1A1 621/4885L3MBTL1 4773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.