SCHEMBL20495657

SCHEMBL20495657

COc1ccc(CNCC(C)NCc2ccc(OC)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.63
KMT2A Q03164 4/20 0.63
L3MBTL1 Q9Y468 1/20 0.55
ANPEP P15144 1/20 0.54
ERAP2 Q6P179 1/20 0.54
CHRM2 P08172 1/20 0.53
HTT P42858 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
CASR P41180 1/20 0.51
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
TSHR P16473 1/20 0.50
DNM1 Q05193 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23367774 0.84 ANPEP (0.58) ANPEPERAP2CHRM2HTTSMN1; SMN2
Hydrochloric Acid SCHEMBL30945857 0.82 ANPEP (0.56) ANPEPERAP2CHRM2HTTSMN1; SMN2
SCHEMBL17238292 0.82 ANPEP (0.56) ANPEPERAP2CHRM2HTTSMN1; SMN2
SCHEMBL19865693 0.82 L3MBTL1 (0.57) MEN1KMT2AL3MBTL1CHRM2HTT
SCHEMBL10263818 0.81 L3MBTL1 (0.56) MEN1KMT2AL3MBTL1HTTSMN1; SMN2
SCHEMBL21245400 0.81 ANPEP (0.63) ANPEPERAP2CHRM2HTTALDH1A1
SCHEMBL20502219 0.81 L3MBTL1 (0.56) MEN1KMT2AL3MBTL1HTTSMN1; SMN2
SCHEMBL17504540 0.81 ANPEP (0.63) ANPEPERAP2CHRM2HTTALDH1A1
SCHEMBL13995687 0.81 ALDH1A1 (0.58) MEN1KMT2AL3MBTL1ANPEPHTT
SCHEMBL696773 0.81 MEN1 (0.58) MEN1KMT2AL3MBTL1CHRM2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230025575-A1 PROCESS FOR PREPARING AMINES OVER A COPPER CATALYST BASF SE (DE) 2023-01-26 US disclosed
EP-4069418-A1 PROCESS FOR PREPARING AMINES OVER A COPPER CATALYST BASF SE (DE) 2022-10-12 EP disclosed
CN-114746179-A Method for producing amines on copper catalysts 巴斯夫欧洲公司 2022-07-12 CN disclosed
US-11225588-B2 Method for producing a curing agent for low-emission epoxy resin compositions SIKA TECHNOLOGY AG (CH) 2022-01-18 US disclosed
EP-3596150-B1 METHOD FOR THE PREPARATION OF A CROSS-LINKER FOR LOW EMISSION EPOXY RESIN COMPOSITIONS SIKA TECH AG (CH) 2021-04-07 EP disclosed
US-20200040215-A1 METHOD FOR PRODUCING A CURING AGENT FOR LOW-EMISSION EPOXY RESIN COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2020-02-06 US disclosed
WO-2018166996-A1 METHOD FOR PRODUCING A CURING AGENT FOR LOW-EMISSION EPOXY RESIN COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2018-09-20 WO disclosed
EP-3375802-A1 METHOD FOR THE PREPARATION OF A CROSS-LINKER FOR LOW EMISSION EPOXY RESIN COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2018-09-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230025575-A1 PROCESS FOR PREPARING AMINES OVER A COPPER CATALYST AOC2, SOD1, AOC3 MEN1 1189/4885KMT2A 224/4885L3MBTL1 3423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.