SCHEMBL20496480

SCHEMBL20496480

CC(C)Oc1ccc(OC(C)C)c(C(=O)c2ccccc2OC(C)C)c1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 2/20 0.58
ALDH1A1 P00352 4/20 0.51
ACHE P22303 1/20 0.47
IDO1 P14902 1/20 0.47
TDO2 P48775 1/20 0.47
KCNK3 O14649 2/20 0.45
KCNK9 Q9NPC2 2/20 0.45
PNLIP P16233 1/20 0.43
ELANE P08246 2/20 0.42
KMT2A Q03164 1/20 0.42
MAPT P10636 2/20 0.41
HTT P42858 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
KDM4E B2RXH2 2/20 0.41
LMNA P02545 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PARP10 Q53GL7 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20496425 0.90 IRAK4 (0.58) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL7088362 0.88 IRAK4 (0.72) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL28694477 0.82 MAPT (0.58) IRAK4ALDH1A1ELANEKMT2AMAPT
SCHEMBL711082 0.80 ALDH1A1 (0.73) IRAK4ALDH1A1KMT2AKDM4EPARP10
SCHEMBL27694472 0.78 IRAK4 (0.64) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL2094692 0.77 IRAK4 (0.72) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL9423987 0.77 MAPT (0.70) ALDH1A1MAPTHTTNPSR1KDM4E
SCHEMBL7195785 0.76 AR (0.57) IRAK4MAPT
SCHEMBL7196731 0.76 IDO1 (0.49) IRAK4ALDH1A1IDO1TDO2KCNK3
SCHEMBL7195790 0.76 AR (0.57) IRAK4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12534548-B2 Bleaching agent, preparation and use of the same with polymerizable compositions for optical materials MITSUI CHEMICALS, INC. (JP) 2026-01-27 US disclosed
US-12448470-B2 Polymerizable composition for optical material, molded product, optical material, and plastic lens and method for manufacturing same MITSUI CHEMICALS, INC. (JP) 2025-10-21 US disclosed
US-20250002724-A1 METHOD FOR MANUFACTURING AN OPTICAL MATERIAL AND COMPOSITION USED IN THIS METHOD MITSUI CHEMICALS, INC. (JP) 2025-01-02 US disclosed
EP-3722840-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, AND MOLDED ARTICLE MITSUI CHEMICALS INC (JP) 2024-12-04 EP disclosed
CN-114599689-B Bleaching agent, preparation thereof and use thereof with polymerizable compositions for optical materials 三井化学株式会社 2024-05-31 CN disclosed
EP-4327139-A1 METHOD FOR MANUFACTURING AN OPTICAL MATERIAL AND COMPOSITION USED IN THIS METHOD Mitsui Chemicals, Inc. (JP) 2024-02-28 EP disclosed
US-20220403065-A1 BLEACHING AGENT, PREPARATION AND USE OF THE SAME WITH POLYMERIZABLE COMPOSITIONS FOR OPTICAL MATERIALS MITSUI CHEMICALS, INC. (JP) 2022-12-22 US disclosed
WO-2022224928-A1 METHOD FOR MANUFACTURING AN OPTICAL MATERIAL AND COMPOSITION USED IN THIS METHOD MITSUI CHEMICALS, INC. (JP) 2022-10-27 WO disclosed
US-11474280-B2 Polymerizable composition for optical material and optical material and plastic lens obtained from same composition MITSUI CHEMICALS, INC. (JP) 2022-10-18 US disclosed
EP-4058490-A1 BLEACHING AGENT, PREPARATION AND USE OF THE SAME WITH POLYMERIZABLE COMPOSITIONS FOR OPTICAL MATERIALS Mitsui Chemicals, Inc. (JP) 2022-09-21 EP disclosed
US-20210230320-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, MOLDED PRODUCT, OPTICAL MATERIAL, AND PLASTIC LENS AND METHOD FOR MANUFACTURING SAME MITSUI CHEMICALS, INC. (JP) 2021-07-29 US disclosed
US-20210171682-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL AND MOLDED PRODUCT MITSUI CHEMICALS, INC. (JP) 2021-06-10 US disclosed
WO-2021095774-A1 BLEACHING AGENT, PREPARATION AND USE OF THE SAME WITH POLYMERIZABLE COMPOSITIONS FOR OPTICAL MATERIALS MITSUI CHEMICALS, INC. (JP) 2021-05-20 WO disclosed
EP-3381951-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, AND OPTICAL MATERIAL AND PLASTIC LENS OBTAINED FROM SAME MITSUI CHEMICALS INC (JP) 2021-04-14 EP disclosed
EP-3722335-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, MOLDED BODY, OPTICAL MATERIAL, PLASTIC LENS, AND PRODUCTION METHOD FOR PLASTIC LENS Mitsui Chemicals, Inc. (JP) 2020-10-14 EP disclosed
EP-3722840-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, AND MOLDED ARTICLE Mitsui Chemicals, Inc. (JP) 2020-10-14 EP disclosed
US-10723862-B2 Polymerizable composition for optical material and optical material and plastic lens obtained from same composition MITSUI CHEMICALS, INC. (JP) 2020-07-28 US disclosed
US-20200233117-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL AND OPTICAL MATERIAL AND PLASTIC LENS OBTAINED FROM SAME COMPOSITION MITSUI CHEMICALS, INC. (JP) 2020-07-23 US disclosed
EP-3381951-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, AND OPTICAL MATERIAL AND PLASTIC LENS OBTAINED FROM SAME Mitsui Chemicals, Inc. (JP) 2018-10-03 EP disclosed
US-20180265674-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL AND OPTICAL MATERIAL AND PLASTIC LENS OBTAINED FROM SAME COMPOSITION Mitsul Chemicals, Inc. (JP) 2018-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534548-B2 Bleaching agent, preparation and use of the same with polymerizable compositions for optical materials HBB, HBZ, CASP12 IRAK4 3921/4885ALDH1A1 1919/4885ACHE 208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.