SCHEMBL2049865

SCHEMBL2049865

Cc1c[c]ccc1-c1cc(F)ccc1F

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 1/20 0.35
SLC9A1 P19634 1/20 0.34
S1PR2 O95136 1/20 0.33
S1PR4 O95977 1/20 0.33
CA3 P07451 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
PTPN1 P18031 1/20 0.32
IDH1 O75874 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2050053 0.86 DPP4 (0.35) NISCH
SCHEMBL2050215 0.79 PTPN1 (0.35) CA3CA6CA5ACA9CA14
SCHEMBL14480559 0.78
SCHEMBL2012045 0.78 ACHE (0.41) NISCHCA9
SCHEMBL2052768 0.76 PDE3B (0.39) CA3CA6CA5ACA9CA14
SCHEMBL6745143 0.76 TNKS2 (0.36) CA9
SCHEMBL2011911 0.76 ACHE (0.36)
SCHEMBL2431965 0.75 AKR1C3 (0.43) NISCH
SCHEMBL2012935 0.74 RAPGEF4 (0.32)
SCHEMBL2012945 0.74 ACHE (0.39) NISCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013182433-A1 A PROCESS USING GRIGNARD REAGENTS BASF SE (DE) 2013-12-12 WO disclosed
EP-2547687-A1 A PROCESS USING GRIGNARD REAGENTS BASF SE (DE) 2013-01-23 EP disclosed
EP-2513067-A1 METHOD FOR PRODUCING TRIAZOLINTHIONE DERIVATIVES AND INTERMEDIATES THEREOF BASF SE (DE) 2012-10-24 EP disclosed
WO-2011073145-A1 METHOD FOR PRODUCING TRIAZOLINTHIONE DERIVATIVES AND INTERMEDIATES THEREOF BASF SE (DE) 2011-06-23 WO disclosed