SCHEMBL20504348

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14551475	1.00	LOXL2 (0.54)	LOXL2MAPTHDAC8HDAC6STAT3
	SCHEMBL13508620	0.90	HDAC8 (0.62)	LOXL2MAPTHDAC8HDAC6STAT3
	SCHEMBL14553477	0.82	HDAC8 (0.50)	LOXL2MAPTHDAC8HDAC6STAT3
	SCHEMBL29110956	0.82	HDAC8 (0.50)	LOXL2MAPTHDAC8HDAC6STAT3
	SCHEMBL21656844	0.82	HDAC8 (0.54)	LOXL2MAPTHDAC8HDAC6CA1
	SCHEMBL5068172	0.82	FFAR1 (0.55)	LOXL2MAPTHDAC8HDAC6STAT3
	SCHEMBL5068169	0.82	FFAR1 (0.55)	LOXL2MAPTHDAC8HDAC6STAT3
	SCHEMBL25334148	0.81	HDAC8 (0.49)	LOXL2MAPTHDAC8HDAC6STAT3
	SCHEMBL15943178	0.80	LOXL2 (0.47)	LOXL2MAPTCA1CA2CA12
	SCHEMBL14551394	0.80	LOXL2 (0.47)	LOXL2MAPTSTAT3CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.