Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30260154 | 0.81 | CA1 (0.47) | MEN1KMT2AKDM1APARP1DRD2 | |
| SCHEMBL26101504 | 0.80 | NNMT (0.44) | MAPKAPK2AKR1C3MEN1KMT2AKDM1A | |
| SCHEMBL20504221 | 0.80 | PRCP (0.53) | MAPKAPK2TSHRAKR1C3MEN1KMT2A | |
| SCHEMBL23304573 | 0.80 | OPRM1 (0.44) | AKR1C3 | |
| SCHEMBL31107143 | 0.77 | KMT2A (0.42) | MAPKAPK2TSHRNPSR1MEN1KMT2A | |
| SCHEMBL1083198 | 0.74 | MAPKAPK2 (0.44) | MAPKAPK2TSHRNPSR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4875139 | 0.74 | MEN1 (0.37) | MAPKAPK2AKR1C3MEN1KMT2AKDM1A | |
| SCHEMBL27969852 | 0.72 | MAPKAPK2 (0.57) | MAPKAPK2TSHRNPSR1MEN1KMT2A | |
| SCHEMBL1013087 | 0.72 | MAOA (0.53) | TSHRMEN1KMT2AMAOAKDM4E | |
| Hydrochloric Acid SCHEMBL9058377 | 0.71 | TSHR (0.46) | TSHRNPSR1MEN1KMT2AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377482-A1 | MODULATORS OF ROR-GAMMA | Vitae Pharmaceuticals, Inc. (US) | 2018-09-26 | — | — | EP | disclosed |