Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 13/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20504355 | 0.80 | MAPKAPK2 (0.44) | AKR1C3 | |
| SCHEMBL26101504 | 0.77 | NNMT (0.44) | AKR1C3 | |
| SCHEMBL20504221 | 0.77 | PRCP (0.53) | F2PLGPLAUKLKB1PRSS1 | |
| SCHEMBL8466120 | 0.73 | KMT2A (0.47) | OPRM1OPRK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4875139 | 0.71 | MEN1 (0.37) | AKR1C3 | |
| SCHEMBL30260154 | 0.70 | CA1 (0.47) | OPRM1OPRK1 | |
| SCHEMBL14591478 | 0.69 | SMN1; SMN2 (0.64) | OPRM1OPRK1SMN1; SMN2OPRD1ALDH1A1 | |
| SCHEMBL1013087 | 0.69 | MAOA (0.53) | ALDH1A1 | |
| SCHEMBL3431402 | 0.69 | SMN1; SMN2 (0.64) | OPRM1OPRK1SMN1; SMN2OPRD1ALDH1A1 | |
| SCHEMBL15071424 | 0.69 | ALDH1A1 (0.52) | OPRM1OPRK1SMN1; SMN2OPRD1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021086879-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2021-05-06 | — | — | WO | disclosed |