Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25184218 | 0.98 | ELANE (0.50) | ELANESRCFNTAFNTBALDH1A1 | |
| SCHEMBL14672258 | 0.97 | ELANE (0.49) | ELANESRCFNTAFNTBALDH1A1 | |
| SCHEMBL20508785 | 0.97 | ELANE (0.49) | ELANESRCFNTAFNTBALDH1A1 | |
| SCHEMBL2553373 | 0.88 | ELANE (0.56) | ELANESRCALDH1A1STSGAA | |
| SCHEMBL28324296 | 0.84 | SRC (0.67) | ELANESRCALDH1A1STSGAA | |
| SCHEMBL14672257 | 0.83 | SRC (0.64) | ELANESRCALDH1A1STSGAA | |
| SCHEMBL1653061 | 0.82 | SRC (0.68) | SRCALDH1A1POLB | |
| Methane SCHEMBL11699189 | 0.81 | SRC (0.65) | SRCALDH1A1POLB | |
| Benzophenone SCHEMBL31236131 | 0.80 | ALDH1A1 (0.64) | ELANESRCFNTAFNTBALDH1A1 | |
| SCHEMBL4103871 | 0.80 | SRC (0.50) | SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10253193-B2 | Photoactivatable crosslinker | SURMODICS, INC. (US) | 2019-04-09 | — | — | US | claimed |
| US-20180273773-A1 | PHOTOACTIVATABLE CROSSLINKER | BANK OF MONTREAL, AS COLLATERAL AGENT | 2018-09-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10253193-B2 | Photoactivatable crosslinker | GLO1, LCP1, PLOD1 | ELANE 3717/4885SRC 1847/4885FNTA 4187/4885 |
| US-20180273773-A1 | PHOTOACTIVATABLE CROSSLINKER | GLO1, LCP1, PLOD1 | ELANE 3717/4885SRC 1847/4885FNTA 4187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.