SCHEMBL2051255

SCHEMBL2051255

CC=CC(C(=O)O)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.35
GRIK1 P39086 4/20 0.31
GRIK2 Q13002 4/20 0.31
GABRP O00591 2/20 0.31
GABRD O14764 2/20 0.31
GABRA1 P14867 2/20 0.31
GABRB1 P18505 2/20 0.31
GABRG2 P18507 2/20 0.31
GABRB3 P28472 2/20 0.31
GABRA5 P31644 2/20 0.31
GABRA3 P34903 2/20 0.31
GABRA2 P47869 2/20 0.31
GABRB2 P47870 2/20 0.31
GABRA4 P48169 2/20 0.31
GABRE P78334 2/20 0.31
GABRA6 Q16445 2/20 0.31
GABRG1 Q8N1C3 2/20 0.31
GABRG3 Q99928 2/20 0.31
GABRQ Q9UN88 2/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2051254 1.00 TP53 (0.35) TP53GRIK1GRIK2GABRPGABRD
SCHEMBL16673754 1.00 TP53 (0.35) TP53GRIK1GRIK2GABRPGABRD
SCHEMBL4847645 0.86 TP53 (0.30) TP53
SCHEMBL18168718 0.80 GRIK1 (0.35) TP53GRIK1GRIK2ALDH1A1
SCHEMBL11119968 0.80 GRIK1 (0.35) TP53GRIK1GRIK2ALDH1A1
SCHEMBL23271215 0.80
SCHEMBL8666643 0.80 SMN1; SMN2 (0.41)
SCHEMBL8000398 0.79 ALDH1A1 (0.38) TP53TSHRLMNAALDH1A1THRB
SCHEMBL11277239 0.76 GABRP (0.30) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL13034089 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020138053-A1 Absorption of water DAN ERVIN (CA) 2002-09-26 US claimed
EP-0862488-A1 ABSORPTION OF WATER CAMELOT SUPERABSORBENTS LTD (CA) 1998-09-09 EP claimed
WO-1997015367-A1 ABSORPTION OF WATER CAMELOT SUPERABSORBENTS LIMITED (CA) 1997-05-01 WO claimed
EP-0012909-B1 BENZIMIDAZOLYL-2-ALKANE-PHOSPHONIC ACIDS AND THEIR SALTS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS CORROSION INHIBITORS OR WETTING AGENTS BAYER AG (DE) 1983-06-15 EP claimed
US-4278791-A CORROSION RESISTANCE, WETTING AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1981-07-14 US claimed
CN-112011129-A Thermoplastic elastomer composition and method for producing same 住友化学株式会社 2020-12-01 CN disclosed
CN-105008483-B Solar cell screening glass and solar battery module 东洋油墨SC控股株式会社 2017-07-14 CN disclosed
EP-2225382-B1 NEW MALONATE DECARBOXYLASES FOR INDUSTRIAL APPLICATIONS BASF SE (DE) 2016-11-09 EP disclosed
CN-101878309-B Malonate decarboxylases for industrial applications BASF SE (DE) 2016-01-13 CN disclosed
US-20150147800-A1 MALONATE DECARBOXYLASES FOR INDUSTRIAL APPLICATIONS BASF SE (DE) 2015-05-28 US disclosed
US-8951750-B2 Malonate decarboxylases for industrial applications BASF SE (DE) 2015-02-10 US disclosed
CN-103890062-A Porous polypropylene film, layered porous film, and electricity-storage device TORAY INDUSTRIES 2014-06-25 CN disclosed
US-4788237-A COPOLYMER CONTAINING CARBOXYLATE SALT, DISPOSABLE DIAPERS ARCO CHEMICAL COMPANY (US) 1988-11-29 US disclosed
EP-0272074-A2 Water-absorbent polymer composition, method of forming it and article containing it CAMELOT SUPERABSORBENTS LTD (CA) 1988-06-22 EP disclosed
US-4743244-A UNSATURATED CARBOXYLIC ACID, ANHYDRIDE, AMIDE, IMIDE, ESTER CONTAINING MONOMER, UNSATURATED COMONOMER, AND POLYETHER ARCO CHEMICAL COMPANY (US) 1988-05-10 US disclosed
EP-0264208-A2 Extended shelf life water-absorbing composition which facilitates fiber formation CAMELOT SUPERABSORBENTS LTD (CA) 1988-04-20 EP disclosed
US-4731067-A DISPOSABLE PRODUCTS ARCO CHEMICAL COMPANY (US) 1988-03-15 US disclosed
EP-0239223-A2 Water-absorbing fiber-forming composition article containing same & method of producing said composition & said article ARCO CHEMICAL TECHNOLOGY, INC. (US) 1987-09-30 EP disclosed
EP-0210754-A1 Water-absorbing polymer composition ARCO CHEMICAL TECHNOLOGY, INC. (US) 1987-02-04 EP disclosed
US-4278791-A CORROSION RESISTANCE, WETTING AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1981-07-14 US disclosed