Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2051255 | 0.86 | TP53 (0.35) | TP53 | |
| SCHEMBL2051254 | 0.86 | TP53 (0.35) | TP53 | |
| SCHEMBL13034089 | 0.86 | — | — | |
| SCHEMBL16673754 | 0.86 | TP53 (0.35) | TP53 | |
| SCHEMBL2553763 | 0.77 | GABRP (0.46) | TP53 | |
| SCHEMBL23271215 | 0.73 | — | — | |
| SCHEMBL8666643 | 0.73 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL7536760 | 0.70 | — | — | |
| SCHEMBL28775457 | 0.70 | FFAR3 (0.39) | TP53FFAR3LCKFYN | |
| SCHEMBL26617402 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439380-B2 | Diarylbutadiene-substituted diorganopolysiloxanes and photoprotective compositions comprised thereof | L'OREAL (FR) | 2008-10-21 | — | — | US | disclosed |
| US-20070213548-A1 | Diarylbutadiene-substituted diorganopolysiloxanes and photoprotective compositions comprised thereof | L'OREAL | 2007-09-13 | — | — | US | disclosed |
| US-7229610-B2 | Diarylbutadiene-substituted diorganopolysiloxanes and photoprotective compositions comprised thereof | L'OREAL (FR) | 2007-06-12 | — | — | US | disclosed |
| US-20050129636-A1 | Diarylbutadiene-substituted diorganopolysiloxanes and photoprotective compositions comprised thereof | L'OREAL (FR) | 2005-06-16 | — | — | US | disclosed |
| EP-0295657-B1 | Metal chelate compound and curable coating composition therefrom | NIPPON PAINT CO LTD (JP) | 1994-01-26 | — | — | EP | disclosed |
| EP-0336428-B1 | CURABLE COMPOSITION | NIPPON PAINT CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |
| US-4983715-A | FROM CARBOXYLIC ANHYDRIDE AND AMINE | NIPPON PAINT CO., LTD. (JP) | 1991-01-08 | — | — | US | disclosed |
| EP-0336428-A2 | Curable composition | NIPPON PAINT CO., LTD. (JP) | 1989-10-11 | — | — | EP | disclosed |
| US-4861839-A | Metal chelate compound and curable coating composition therefrom | NIPPON PAINT CO., LTD. (JP) | 1989-08-29 | — | — | US | disclosed |
| EP-0295657-A2 | Metal chelate compound and curable coating composition therefrom | Nippon Paint Co., Ltd. (JP) | 1988-12-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213548-A1 | Diarylbutadiene-substituted diorganopolysiloxanes and photoprotective compositions comprised thereof | XPA, ERCC4, DCLRE1A | TP53 2131/4885FFAR3 4010/4885LCK 4815/4885 |
| US-20050129636-A1 | Diarylbutadiene-substituted diorganopolysiloxanes and photoprotective compositions comprised thereof | XPA, ERCC4, DCLRE1A | TP53 2131/4885FFAR3 4010/4885LCK 4815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.