Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9240092 | 0.74 | MTNR1A (0.50) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL9238577 | 0.74 | MTNR1A (0.48) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| Hydrochloric Acid SCHEMBL9237392 | 0.73 | MTNR1A (0.47) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| Hydrochloric Acid SCHEMBL9238517 | 0.73 | MTNR1A (0.49) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL2025141 | 0.70 | DRD2 (0.59) | CHRM2CHRM1CHRM3DRD2 | |
| SCHEMBL2024065 | 0.70 | DRD2 (0.59) | CHRM2CHRM1CHRM3DRD2 | |
| SCHEMBL2024495 | 0.70 | DRD2 (0.59) | CHRM2CHRM1CHRM3DRD2 | |
| SCHEMBL3732776 | 0.70 | SIGMAR1 (0.54) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 | |
| SCHEMBL12634890 | 0.70 | CHRM2 (0.60) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL8972304 | 0.69 | MTNR1A (0.49) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516383-A1 | NEW AMINOTETRALINE DERIVATIVES | Gmeiner, Peter (DE) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011076708-A1 | NEW AMINOTETRALINE DERIVATIVES | GMEINER PETER (DE) | 2011-06-30 | — | — | WO | disclosed |