Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2399432 | 0.73 | ALDH1A1 (0.43) | ALDH1A1TSHRPOLBLMNAHTT | |
| SCHEMBL31493403 | 0.72 | AR (0.47) | ALDH1A1TSHRPOLBLMNA | |
| SCHEMBL6819794 | 0.69 | AR (0.45) | ALDH1A1POLB | |
| SCHEMBL5889531 | 0.65 | GAA (0.39) | ALDH1A1TSHRPOLBLMNAHTT | |
| SCHEMBL1841466 | 0.64 | SIGMAR1 (0.37) | TDP1LMNAHTT | |
| SCHEMBL9956839 | 0.62 | DRD2 (0.36) | LMNA | |
| SCHEMBL11673012 | 0.61 | ALDH1A1 (0.48) | ALDH1A1TSHRTDP1KDM4ELMNA | |
| SCHEMBL1842086 | 0.61 | KMT2A (0.43) | ALDH1A1POLBLMNAHTT | |
| SCHEMBL1662655 | 0.61 | AR (0.51) | ALDH1A1TSHRPOLBTDP1 | |
| SCHEMBL12438322 | 0.61 | MAPK1 (0.44) | ALDH1A1TSHRPOLBLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018177863-A1 | DERIVATIVES OF THE DISODIUM 2,2'-{CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(1-METHYL-1H-PYRROLE-4,2-DIYL) CARBONYLIMINO]}DINAPHTHALENE-1,5-DISULFONATE SALT AND RELATED COMPOUNDS AS HEPARANASE INHIBITORS FOR THE TREATMENT OF CANCER | LEADIANT BIOSCIENCES SA IN LIQUIDAZIONE (CH) | 2018-10-04 | — | — | WO | disclosed |
| EP-3381897-A1 | DERIVATIVES OF THE DISODIUM 2,2'-{CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(1-METHYL-1H-PYRROLE-4,2-DIYL)CARBONYLIMINO]}DINAPHTHALENE-1,5-DISULFONATE SALT AND RELATED COMPOUNDS AS HEPARANASE INHIBITORS FOR THE TREATMENT OF CANCER | Leadiant Biosciences SA (CH) | 2018-10-03 | — | — | EP | disclosed |