Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1844382 | 0.99 | NPC1 (0.46) | ARNPC1CASP3KMT2AMAPT | |
| SCHEMBL6819794 | 0.94 | AR (0.45) | ARNPC1CASP3KMT2AMAPT | |
| SCHEMBL31493404 | 0.81 | KMT2A (0.48) | CASP3KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL1847823 | 0.79 | ALDH1A1 (0.37) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1298878 | 0.78 | NPC1 (0.52) | ARNPC1KMT2AMAPTPOLB | |
| SCHEMBL1844219 | 0.77 | AR (0.46) | ARNPC1CASP3MAPTALDH1A1 | |
| SCHEMBL3477514 | 0.76 | AR (0.57) | ARNPC1MAPTPOLBCACNA1F | |
| SCHEMBL30211543 | 0.73 | NPC1 (0.48) | ARNPC1KMT2AMAPTPOLB | |
| SCHEMBL6825077 | 0.73 | AR (0.45) | ARNPC1MAPTALDH1A1CACNA1F | |
| SCHEMBL1842078 | 0.73 | NPC1 (0.47) | ARNPC1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076236-A1 | METHODS AND COMPOUNDS FOR MODULATING HUNTINGTON'S DISEASE | Design Therapeutics, Inc. (US) | 2025-04-10 | — | — | WO | disclosed |