Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20514969 | 1.00 | SMN1; SMN2 (0.60) | SMN1; SMN2HTTL3MBTL1MEN1KMT2A | |
| SCHEMBL5967053 | 0.93 | ALDH1A1 (0.53) | SMN1; SMN2HTTL3MBTL1MEN1KMT2A | |
| SCHEMBL28609758 | 0.86 | ALDH1A1 (0.61) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL20514985 | 0.86 | SMN1; SMN2 (0.54) | SMN1; SMN2HTTL3MBTL1MEN1KMT2A | |
| SCHEMBL20514983 | 0.86 | SMN1; SMN2 (0.54) | SMN1; SMN2HTTL3MBTL1MEN1KMT2A | |
| SCHEMBL5967356 | 0.85 | SMN1; SMN2 (0.58) | SMN1; SMN2HTTL3MBTL1MEN1KMT2A | |
| SCHEMBL20515051 | 0.85 | SMN1; SMN2 (0.58) | SMN1; SMN2HTTL3MBTL1MEN1KMT2A | |
| SCHEMBL4156603 | 0.85 | ATM (0.65) | MEN1KMT2AALDH1A1ATMLMNA | |
| SCHEMBL4156601 | 0.85 | ATM (0.65) | MEN1KMT2AALDH1A1ATMLMNA | |
| SCHEMBL5967074 | 0.83 | NLRP3 (0.46) | SMN1; SMN2HTTL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3381898-A1 | SYMMETRICAL TRIS-ARYL-AMIDE DERIVATIVES AND THEIR USE AS ANTI-HEPARANASE | Leadiant Biosciences SA (CH) | 2018-10-03 | — | — | EP | disclosed |