Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 2/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2827455 | 0.79 | TP53 (0.40) | LMNAHTTALDH1A1GAA | |
| Methoxymethane SCHEMBL28298291 | 0.69 | ITGB2 (0.38) | LMNACRHBPCRHR2SMN1; SMN2HTT | |
| Benzene SCHEMBL27610541 | 0.69 | ITGB2 (0.48) | LMNACRHBPCRHR2SMN1; SMN2HTT | |
| SCHEMBL456419 | 0.69 | ITGB2 (0.45) | LMNACRHBPCRHR2SMN1; SMN2HTT | |
| SCHEMBL33274 | 0.69 | — | — | |
| SCHEMBL15981877 | 0.67 | LMNA (0.52) | LMNACRHBPCRHR2SMN1; SMN2HTT | |
| SCHEMBL15981871 | 0.67 | LMNA (0.52) | LMNACRHBPCRHR2SMN1; SMN2HTT | |
| SCHEMBL14587292 | 0.67 | LMNA (0.52) | LMNACRHBPCRHR2SMN1; SMN2HTT | |
| SCHEMBL15982300 | 0.67 | LMNA (0.52) | LMNACRHBPCRHR2SMN1; SMN2HTT | |
| SCHEMBL14587294 | 0.67 | LMNA (0.52) | LMNACRHBPCRHR2SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10821429-B2 | Precatalysts and process for the metal-free functionalization of SP2 carbons using the same | UNIVERSITé LAVAL (CA) | 2020-11-03 | — | — | US | disclosed |
| US-20190262817-A1 | PRECATALYSTS AND PROCESS FOR THE METAL-FREE FUNCTIONALIZATION OF SP2 CARBONS USING THE SAME | UNIVERSITé LAVAL (CA) | 2019-08-29 | — | — | US | disclosed |
| US-10258976-B2 | Precatalysts and process for the metal-free functionalization of SP2 carbons using the same | UNIVERSITé LAVAL (CA) | 2019-04-16 | — | — | US | disclosed |
| EP-3389859-A1 | PRECATALYSTS AND PROCESS FOR THE METAL-FREE FUNCTIONALIZATION OF SP2 CARBONS USING THE SAME | Université Laval (CA) | 2018-10-24 | — | — | EP | disclosed |
| US-20180280950-A1 | PRECATALYSTS AND PROCESS FOR THE METAL-FREE FUNCTIONALIZATION OF SP2 CARBONS USING THE SAME | UNIVERSITE LAVAL (CA) | 2018-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10258976-B2 | Precatalysts and process for the metal-free functionalization of SP2 carbons using the same | SP1, LEF1, FOS | LMNA 515/4885CRHBP 3816/4885CRHR2 3210/4885 |
| US-20180280950-A1 | PRECATALYSTS AND PROCESS FOR THE METAL-FREE FUNCTIONALIZATION OF SP2 CARBONS USING THE SAME | SP1, LEF1, FOS | LMNA 515/4885CRHBP 3816/4885CRHR2 3210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.